The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mitochondrial carrier domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 81: NAD+ transporter

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NAD transmembrane transporter activity GO:0051724
Enables the transfer of NAD from one side of a membrane to the other.
14 P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P40556 (/IGI)
(4 more)
NAD transmembrane transporter activity GO:0051724
Enables the transfer of NAD from one side of a membrane to the other.
14 P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P40556 (/IMP)
(4 more)
NAD transmembrane transporter activity GO:0051724
Enables the transfer of NAD from one side of a membrane to the other.
9 P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS)
Pyruvate secondary active transmembrane transporter activity GO:0005477
Enables the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
5 P40556 (/IMP) P40556 (/IMP) P40556 (/IMP) P40556 (/IMP) P40556 (/IMP)
NAD transmembrane transporter activity GO:0051724
Enables the transfer of NAD from one side of a membrane to the other.
5 P40556 (/IDA) P40556 (/IDA) P40556 (/IDA) P40556 (/IDA) P40556 (/IDA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
NAD transmembrane transport GO:0035352
The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH.
14 P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P39953 (/IGI) P40556 (/IGI)
(4 more)
NAD transmembrane transport GO:0035352
The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH.
14 P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P39953 (/IMP) P40556 (/IMP)
(4 more)
NAD transmembrane transport GO:0035352
The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH.
9 P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS)
Mitochondrial pyruvate transmembrane transport GO:0006850
The process in which pyruvate is transported across a mitochondrial membrane, into or out of the mitochondrion.
5 P40556 (/IMP) P40556 (/IMP) P40556 (/IMP) P40556 (/IMP) P40556 (/IMP)
NAD transmembrane transport GO:0035352
The process in which a nicotinamide adenine dinucleotide is transported across a membrane; transport may be of either the oxidized form, NAD, or the reduced form, NADH.
5 P40556 (/IDA) P40556 (/IDA) P40556 (/IDA) P40556 (/IDA) P40556 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
14 P39953 (/HDA) P39953 (/HDA) P39953 (/HDA) P39953 (/HDA) P39953 (/HDA) P39953 (/HDA) P39953 (/HDA) P39953 (/HDA) P39953 (/HDA) P40556 (/HDA)
(4 more)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
9 P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS) P39953 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 P40556 (/IDA) P40556 (/IDA) P40556 (/IDA) P40556 (/IDA) P40556 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...