The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Mitochondrial carrier domain
".
FunFam 7: Mitochondrial tricarboxylate transport protein-lik...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Tricarboxylate secondary active transmembrane transporter activity GO:0005371
Enables the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
|
6 | P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) |
|
Citrate transmembrane transporter activity GO:0015137
Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other.
|
2 | P32089 (/TAS) P53007 (/TAS) |
|
Tricarboxylic acid transmembrane transporter activity GO:0015142
Enables the transfer of tricarboxylic acids from one side of a membrane to the other. Tricarboxylic acid are organic acids with three COOH groups.
|
1 | P53007 (/TAS) |
|
Citrate secondary active transmembrane transporter activity GO:0071913
Enables the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.
|
1 | P53007 (/IDA) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrial citrate transmembrane transport GO:0006843
The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into or out of a mitochondrial matrix.
|
6 | P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) |
|
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
|
6 | P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) P38152 (/IDA) |
|
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
|
1 | P53007 (/TAS) |
|
Mitochondrial citrate transmembrane transport GO:0006843
The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into or out of a mitochondrial matrix.
|
1 | Q7KSQ0 (/IMP) |
|
Mitochondrial citrate transmembrane transport GO:0006843
The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into or out of a mitochondrial matrix.
|
1 | P32089 (/TAS) |
|
Neuromuscular junction development GO:0007528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
|
1 | Q6PGY3 (/IMP) |
|
Regulation of mitochondrion organization GO:0010821
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
|
1 | Q6PGY3 (/IMP) |
|
Citrate transport GO:0015746
The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q7KSQ0 (/IDA) |
|
Fatty-acyl-CoA biosynthetic process GO:0046949
The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
|
1 | P53007 (/TAS) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
7 | P38152 (/HDA) P38152 (/HDA) P38152 (/HDA) P38152 (/HDA) P38152 (/HDA) P38152 (/HDA) Q8JZU2 (/HDA) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
6 | P38152 (/IC) P38152 (/IC) P38152 (/IC) P38152 (/IC) P38152 (/IC) P38152 (/IC) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q7KSQ0 (/IDA) Q8JZU2 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | A0A1D8PJV4 (/IDA) A0A1D8PJV4 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P53007 (/HDA) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q8JZU2 (/HDA) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | P53007 (/TAS) |
|
Nebenkern GO:0016006
A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme.
|
1 | Q7KSQ0 (/IDA) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | P53007 (/HDA) |
