The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mitochondrial carrier domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 35: Mitochondrial carrier homolog 2 variant

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein localization to mitochondrion GO:0070585
A process in which a protein is transported to, or maintained in, a location within the mitochondrion.
6 Q791V5 (/IMP) Q9Y6C9 (/IMP) Q9Y6C9 (/IMP) Q9Y6C9 (/IMP) Q9Y6C9 (/IMP) Q9Y6C9 (/IMP)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
1 Q9PUL9 (/IMP)
Lactate metabolic process GO:0006089
The chemical reactions and pathways involving lactate, the anion of lactic acid.
1 Q791V5 (/IMP)
Negative regulation of mitochondrial membrane potential GO:0010917
Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
1 Q791V5 (/IMP)
Hematopoietic stem cell migration GO:0035701
The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
1 Q791V5 (/IMP)
Mitochondrial ATP synthesis coupled electron transport GO:0042775
The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane.
1 Q791V5 (/IMP)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280
Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
1 Q791V5 (/IMP)
Fat cell differentiation GO:0045444
The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
1 Q9PUL9 (/IMP)
Negative regulation of glycolytic process GO:0045820
Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis.
1 Q791V5 (/IMP)
Digestive tract development GO:0048565
The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
1 Q9PUL9 (/IMP)
Hematopoietic stem cell homeostasis GO:0061484
Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.
1 Q791V5 (/IMP)
Protein localization to mitochondrion GO:0070585
A process in which a protein is transported to, or maintained in, a location within the mitochondrion.
1 Q791V5 (/ISO)
Cellular response to radiation GO:0071478
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
1 Q791V5 (/IMP)
Establishment of protein localization to mitochondrial membrane involved in mitochondrial fission GO:0090152
The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission.
1 Q791V5 (/IMP)
Hepatocyte apoptotic process GO:0097284
Any apoptotic process in a hepatocyte, the main structural component of the liver.
1 Q791V5 (/IGI)
Regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108
Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.
1 Q791V5 (/IGI)
Positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage GO:1902231
Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.
1 Q791V5 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q9Y6C9 (/HDA) Q9Y6C9 (/HDA) Q9Y6C9 (/HDA) Q9Y6C9 (/HDA) Q9Y6C9 (/HDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
5 Q9Y6C9 (/HDA) Q9Y6C9 (/HDA) Q9Y6C9 (/HDA) Q9Y6C9 (/HDA) Q9Y6C9 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q791V5 (/HDA)
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
1 Q791V5 (/IDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
1 Q791V5 (/HDA)
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