The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mitochondrial carrier domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 25: mitochondrial folate transporter/carrier

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Folic acid transmembrane transporter activity GO:0008517
Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
3 Q9H2D1 (/ISS) Q9H2D1 (/ISS) Q9H2D1 (/ISS)
Folic acid transmembrane transporter activity GO:0008517
Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
3 Q9H2D1 (/NAS) Q9H2D1 (/NAS) Q9H2D1 (/NAS)
Folic acid transmembrane transporter activity GO:0008517
Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
3 Q9H2D1 (/TAS) Q9H2D1 (/TAS) Q9H2D1 (/TAS)
Folic acid transmembrane transporter activity GO:0008517
Enables the transfer of folic acid (pteroylglutamic acid) from one side of a membrane to the other. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
1 Q6IZB5 (/IMP)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Glycine metabolic process GO:0006544
The chemical reactions and pathways involving glycine, aminoethanoic acid.
3 Q9H2D1 (/IGI) Q9H2D1 (/IGI) Q9H2D1 (/IGI)
Glycine metabolic process GO:0006544
The chemical reactions and pathways involving glycine, aminoethanoic acid.
3 Q9H2D1 (/ISS) Q9H2D1 (/ISS) Q9H2D1 (/ISS)
Folic acid transport GO:0015884
The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
3 Q9H2D1 (/NAS) Q9H2D1 (/NAS) Q9H2D1 (/NAS)
Folic acid metabolic process GO:0046655
The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
3 Q9H2D1 (/TAS) Q9H2D1 (/TAS) Q9H2D1 (/TAS)
Folate import into mitochondrion GO:1904947
The process in which folic acid is transported from the cytosol, into the mitochondrial matrix.
3 Q9H2D1 (/ISS) Q9H2D1 (/ISS) Q9H2D1 (/ISS)
Glycine metabolic process GO:0006544
The chemical reactions and pathways involving glycine, aminoethanoic acid.
1 Q6IZB5 (/IMP)
Glycine metabolic process GO:0006544
The chemical reactions and pathways involving glycine, aminoethanoic acid.
1 Q8BMG8 (/ISO)
Folate import into mitochondrion GO:1904947
The process in which folic acid is transported from the cytosol, into the mitochondrial matrix.
1 Q6IZB5 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
4 Q6IZB5 (/NAS) Q9H2D1 (/NAS) Q9H2D1 (/NAS) Q9H2D1 (/NAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 Q9H2D1 (/IDA) Q9H2D1 (/IDA) Q9H2D1 (/IDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
3 Q9H2D1 (/TAS) Q9H2D1 (/TAS) Q9H2D1 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8BMG8 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8BMG8 (/ISO)
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