The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mitochondrial carrier domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 20: mitochondrial uncoupling protein 4 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
4 Q6R5J6 (/IDA) Q9EPH5 (/IDA) Q9EPH6 (/IDA) Q9EPH7 (/IDA)
Negative regulation of mitochondrial membrane potential GO:0010917
Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
4 Q6R5J6 (/IDA) Q9EPH5 (/IDA) Q9EPH6 (/IDA) Q9EPH7 (/IDA)
Cellular triglyceride homeostasis GO:0035356
Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment.
4 Q6R5J6 (/IDA) Q9EPH5 (/IDA) Q9EPH6 (/IDA) Q9EPH7 (/IDA)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
4 Q6R5J6 (/IDA) Q9EPH5 (/IDA) Q9EPH6 (/IDA) Q9EPH7 (/IDA)
Regulation of glucose import GO:0046324
Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
4 Q6R5J6 (/IDA) Q9EPH5 (/IDA) Q9EPH6 (/IDA) Q9EPH7 (/IDA)
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
4 Q6R5J6 (/IEP) Q9EPH5 (/IEP) Q9EPH6 (/IEP) Q9EPH7 (/IEP)
Negative regulation of mitochondrial calcium ion concentration GO:0051562
Any process that decreases the concentration of calcium ions in mitochondria.
4 Q6R5J6 (/IMP) Q9EPH5 (/IMP) Q9EPH6 (/IMP) Q9EPH7 (/IMP)
Neuron death GO:0070997
The process of cell death in a neuron.
4 Q6R5J6 (/IMP) Q9EPH5 (/IMP) Q9EPH6 (/IMP) Q9EPH7 (/IMP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 Q9CX10 (/ISO) Q9D6D0 (/ISO)
Negative regulation of mitochondrial membrane potential GO:0010917
Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
2 Q9CX10 (/ISO) Q9D6D0 (/ISO)
Cellular triglyceride homeostasis GO:0035356
Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment.
2 Q9CX10 (/ISO) Q9D6D0 (/ISO)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
2 Q9CX10 (/ISO) Q9D6D0 (/ISO)
Regulation of glucose import GO:0046324
Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
2 Q9CX10 (/ISO) Q9D6D0 (/ISO)
Negative regulation of mitochondrial calcium ion concentration GO:0051562
Any process that decreases the concentration of calcium ions in mitochondria.
2 Q9CX10 (/ISO) Q9D6D0 (/ISO)
Neuron death GO:0070997
The process of cell death in a neuron.
2 Q9CX10 (/ISO) Q9D6D0 (/ISO)
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
2 O95847 (/TAS) O95847 (/TAS)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 O95847 (/IDA) O95847 (/IDA) Q9CX10 (/IDA) Q9D6D0 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
4 Q6R5J6 (/IDA) Q9EPH5 (/IDA) Q9EPH6 (/IDA) Q9EPH7 (/IDA)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
4 Q6R5J6 (/IDA) Q9EPH5 (/IDA) Q9EPH6 (/IDA) Q9EPH7 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q9CX10 (/HDA) Q9D6D0 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q9CX10 (/ISO) Q9D6D0 (/ISO)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
2 O95847 (/TAS) O95847 (/TAS)
Mitochondrial membrane GO:0031966
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
2 O95847 (/IDA) O95847 (/IDA)
Mitochondrial membrane GO:0031966
Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
2 Q9CX10 (/ISO) Q9D6D0 (/ISO)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 Q9CX10 (/ISO) Q9D6D0 (/ISO)
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
2 Q9CX10 (/ISO) Q9D6D0 (/ISO)
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