The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Mitochondrial carrier domain
".
FunFam 13: Mitochondrial 2-oxoglutarate/malate carrier protei...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
5 | Q02978 (/HDA) Q02978 (/HDA) Q02978 (/HDA) Q02978 (/HDA) Q02978 (/HDA) |
|
Oxoglutarate:malate antiporter activity GO:0015367
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out).
|
5 | Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) |
|
Oxoglutarate:malate antiporter activity GO:0015367
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out).
|
4 | Q8SXB4 (/ISS) Q9VAJ9 (/ISS) Q9VZ93 (/ISS) Q9VZ94 (/ISS) |
|
Alpha-ketoglutarate transmembrane transporter activity GO:0015139
Enables the transfer of alpha-ketoglutarate from one side of a membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.
|
2 | Q9CR62 (/ISO) Q9CR62 (/ISO) |
There are 4 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Gluconeogenesis GO:0006094
The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
|
5 | Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) |
|
Mitochondrial transport GO:0006839
Transport of substances into, out of or within a mitochondrion.
|
4 | Q8SXB4 (/ISS) Q9VAJ9 (/ISS) Q9VZ93 (/ISS) Q9VZ94 (/ISS) |
|
Alpha-ketoglutarate transport GO:0015742
The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
4 | Q8SXB4 (/ISS) Q9VAJ9 (/ISS) Q9VZ93 (/ISS) Q9VZ94 (/ISS) |
|
Malate transport GO:0015743
The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
4 | Q8SXB4 (/ISS) Q9VAJ9 (/ISS) Q9VZ93 (/ISS) Q9VZ94 (/ISS) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
8 | Q02978 (/HDA) Q02978 (/HDA) Q02978 (/HDA) Q02978 (/HDA) Q02978 (/HDA) Q9CR62 (/HDA) Q9CR62 (/HDA) Q9VAJ9 (/HDA) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
6 | P22292 (/ISS) P22292 (/ISS) Q8SXB4 (/ISS) Q9VAJ9 (/ISS) Q9VZ93 (/ISS) Q9VZ94 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | Q02978 (/HDA) Q02978 (/HDA) Q02978 (/HDA) Q02978 (/HDA) Q02978 (/HDA) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
5 | Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) Q02978 (/TAS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q9CR62 (/ISO) Q9CR62 (/ISO) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | P22292 (/ISS) P22292 (/ISS) |
|
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
2 | Q9CR62 (/HDA) Q9CR62 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | P90992 (/IDA) |
