The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Mitochondrial carrier domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 11: Mitochondrial thiamine pyrophosphate carrier 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thiamine pyrophosphate transmembrane transporter activity GO:0090422
Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other.
3 Q8RXZ9 (/IGI) Q9FI73 (/IGI) Q9FI73 (/IGI)
Deoxynucleotide transmembrane transporter activity GO:0030233
Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP.
2 Q9HC21 (/TAS) Q9HC21 (/TAS)
Thiamine pyrophosphate transmembrane transporter activity GO:0090422
Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other.
2 A0A1D6N272 (/IDA) B4FIJ0 (/IDA)
Thiamine pyrophosphate transmembrane transporter activity GO:0090422
Enables the transfer of thiamine pyrophosphate a substance from one side of a membrane to the other.
2 Q9HC21 (/TAS) Q9HC21 (/TAS)
Thiamine transmembrane transporter activity GO:0015234
Enables the transfer of thiamine from one side of a membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
1 Q7K0L7 (/IDA)
Antiporter activity GO:0015297
Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
1 Q7K0L7 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thiamine pyrophosphate transmembrane transport GO:0030974
The process in which thiamine pyrophosphate is transported across a membrane.
3 A0A1D6N272 (/IDA) B4FIJ0 (/IDA) Q7K0L7 (/IDA)
Thiamine pyrophosphate transmembrane transport GO:0030974
The process in which thiamine pyrophosphate is transported across a membrane.
3 Q8RXZ9 (/IGI) Q9FI73 (/IGI) Q9FI73 (/IGI)
Deoxynucleotide transport GO:0030302
The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell.
2 Q9HC21 (/NAS) Q9HC21 (/NAS)
Thiamine-containing compound metabolic process GO:0042723
The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.
2 Q9HC21 (/TAS) Q9HC21 (/TAS)
Thiamine pyrophosphate transmembrane transport GO:0030974
The process in which thiamine pyrophosphate is transported across a membrane.
1 B4FIJ0 (/IMP)
Mitochondrial thiamine pyrophosphate transmembrane transport GO:1990545
The process in which thiamine pyrophosphate is transported across a mitochondrial membrane, into or out of the mitochondrion.
1 Q7K0L7 (/IGI)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 A0A1D6N272 (/IDA) B4FIJ0 (/IDA) Q8RXZ9 (/IDA) Q9FI73 (/IDA) Q9FI73 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9HC21 (/HDA) Q9HC21 (/HDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
2 Q9HC21 (/TAS) Q9HC21 (/TAS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9DAM5 (/HDA)
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