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CATH Superfamily 1.50.10.130

Terpene synthase, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Terpene synthase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6: Terpene synthase 7

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Geranyllinalool synthase. [EC: 4.2.3.144]
Geranylgeranyl diphosphate + H(2)O = (E,E)-geranyllinalool + diphosphate.
  • The enzyme is a component of the herbivore-induced indirect defense system.
  • The product, (E,E)-geranyllinalool, is a precursor to the volatile compound 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT), which is released by many plants in response to damage.
 1 Q29VN2
S-linalool synthase. [EC: 4.2.3.25]
Geranyl diphosphate + H(2)O = (3S)-linalool + diphosphate.
  • Neither (S)- nor (R)-linalyl diphosphate can act as substrate for the enzyme from Clarkia breweri.
  • Unlike many other monoterpene synthases, only a single product, (3S)- linalool, is formed.
 1 Q29VN2
(3S,6E)-nerolidol synthase. [EC: 4.2.3.48]
(2E,6E)-farnesyl diphosphate + H(2)O = (3S,6E)-nerolidol + diphosphate.
  • The enzyme catalyzes a step in the formation of 4,8-dimethyl- 1,3(E),7-nonatriene, a key signal molecule in induced plant defense mediated by the attraction of enemies of herbivores (2).
  • Nerolidol is a naturally occurring sesquiterpene found in the essential oils of many types of plants.
 1 Q29VN2
Alpha-farnesene synthase. [EC: 4.2.3.46]
(2E,6E)-farnesyl diphosphate = (3E,6E)-alpha-farnesene + diphosphate.
    		 1 B9RXW0