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CATH Superfamily 1.50.10.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 23: Protein-glucosylgalactosylhydroxylysine glucosidas...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Protein-glucosylgalactosylhydroxylysine glucosidase. [EC: 3.2.1.107]
Protein alpha-D-glucosyl-(1->2)-beta-D-galactosyl-L-hydroxylysine + H(2)O = D-glucose + protein beta-D-galactosyl-L-hydroxylysine.
  • The enzyme specifically hydrolyzes glucose from alpha-D-glucosyl- (1->2)-beta-D-galactosyl disaccharide units that are linked to hydroxylysine residues of collagen and collagen-like proteins.
  • Acetylation of the epsilon-amino group of the glycosylated hydroxylysine abolishes activity.
 8 A0A024R1Z9 A0A024R1Z9 A0JMP0 F1NZI4 Q32M88 Q32M88 Q54KX5 Q8BP56
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