The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Regulation of nuclear pre-mRNA domain-containing p...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
83 Q96P16 (/IPI) Q96P16 (/IPI) Q96P16 (/IPI) Q96P16 (/IPI) Q96P16 (/IPI) Q96P16 (/IPI) Q96P16 (/IPI) Q96P16 (/IPI) Q96P16 (/IPI) Q96P16 (/IPI)
(73 more)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
49 Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA)
(39 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
49 Q9NQG5 (/IPI) Q9NQG5 (/IPI) Q9NQG5 (/IPI) Q9NQG5 (/IPI) Q9NQG5 (/IPI) Q9NQG5 (/IPI) Q9NQG5 (/IPI) Q9NQG5 (/IPI) Q9NQG5 (/IPI) Q9NQG5 (/IPI)
(39 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 Q8VDS4 (/ISO) Q9CSU0 (/ISO) Q9CSU0 (/ISO)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
2 Q9CSU0 (/ISO) Q9CSU0 (/ISO)
RNA polymerase II complex binding GO:0000993
Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
2 Q9CSU0 (/ISS) Q9CSU0 (/ISS)

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
SnRNA transcription by RNA polymerase II GO:0042795
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
83 Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS)
(73 more)
Dephosphorylation of RNA polymerase II C-terminal domain GO:0070940
The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.
83 Q96P16 (/IMP) Q96P16 (/IMP) Q96P16 (/IMP) Q96P16 (/IMP) Q96P16 (/IMP) Q96P16 (/IMP) Q96P16 (/IMP) Q96P16 (/IMP) Q96P16 (/IMP) Q96P16 (/IMP)
(73 more)
Dephosphorylation of RNA polymerase II C-terminal domain GO:0070940
The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.
72 Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS)
(62 more)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
49 Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA)
(39 more)
Regulation of cell cycle process GO:0010564
Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
49 Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA)
(39 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
49 Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA)
(39 more)
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
3 Q9VJ77 (/ISS) X2JAA3 (/ISS) X2JEK7 (/ISS)
Dephosphorylation of RNA polymerase II C-terminal domain GO:0070940
The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.
3 Q8VDS4 (/ISO) Q9CSU0 (/ISO) Q9CSU0 (/ISO)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 Q9CSU0 (/ISO) Q9CSU0 (/ISO)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 Q9CSU0 (/ISS) Q9CSU0 (/ISS)
Regulation of cell cycle process GO:0010564
Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
2 Q9CSU0 (/ISO) Q9CSU0 (/ISO)
Regulation of cell cycle process GO:0010564
Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
2 Q9CSU0 (/ISS) Q9CSU0 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 Q9CSU0 (/ISO) Q9CSU0 (/ISO)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 Q9CSU0 (/ISS) Q9CSU0 (/ISS)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
83 Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS) Q96P16 (/TAS)
(73 more)
RNA polymerase II, holoenzyme GO:0016591
A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters.
83 Q96P16 (/IDA) Q96P16 (/IDA) Q96P16 (/IDA) Q96P16 (/IDA) Q96P16 (/IDA) Q96P16 (/IDA) Q96P16 (/IDA) Q96P16 (/IDA) Q96P16 (/IDA) Q96P16 (/IDA)
(73 more)
RNA polymerase II, holoenzyme GO:0016591
A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters.
72 Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS) Q0P5J9 (/ISS)
(62 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
49 Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA)
(39 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
49 Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA)
(39 more)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
49 Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA)
(39 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
49 Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA) Q9NQG5 (/IDA)
(39 more)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
3 Q9VJ77 (/ISS) X2JAA3 (/ISS) X2JEK7 (/ISS)
RNA polymerase II, holoenzyme GO:0016591
A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters.
3 Q8VDS4 (/ISO) Q9CSU0 (/ISO) Q9CSU0 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9CSU0 (/ISO) Q9CSU0 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9CSU0 (/ISS) Q9CSU0 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 Q9CSU0 (/ISO) Q9CSU0 (/ISO)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
2 Q9CSU0 (/ISO) Q9CSU0 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 Q9CSU0 (/ISO) Q9CSU0 (/ISO)
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