The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 10: EH domain binding protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 Q05785 (/IPI) Q05785 (/IPI) Q12518 (/IPI) Q12518 (/IPI) Q12518 (/IPI) Q12518 (/IPI) Q12518 (/IPI) Q12518 (/IPI) Q12518 (/IPI)
Clathrin binding GO:0030276
Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.
7 Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA)
Ubiquitin binding GO:0043130
Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
7 Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA)
Clathrin binding GO:0030276
Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.
3 G4MSW7 (/ISS) Q05785 (/ISS) Q05785 (/ISS)
Phosphatidylinositol-4,5-bisphosphate binding GO:0005546
Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
1 O74423 (/IDA)
Clathrin binding GO:0030276
Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.
1 O74423 (/ISO)
Ubiquitin binding GO:0043130
Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
1 O74423 (/ISM)

There are 8 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
10 O74423 (/IMP) Q05785 (/IMP) Q05785 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
10 O74423 (/IMP) Q05785 (/IMP) Q05785 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP)
Actin cortical patch assembly GO:0000147
Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
9 Q05785 (/IMP) Q05785 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP) Q12518 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
3 Q4WLR7 (/IMP) Q4WLR7 (/IMP) Q4WLR7 (/IMP)
Actin cortical patch assembly GO:0000147
Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
1 O74423 (/ISO)
Actin cortical patch assembly GO:0000147
Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
1 G4MSW7 (/ISS)
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
1 G4MSW7 (/ISS)
Actin filament organization GO:0007015
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
1 G4MSW7 (/ISS)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mating projection tip GO:0043332
The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
9 Q05785 (/HDA) Q05785 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7 Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA)
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
7 Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA) Q12518 (/IDA)
Cellular bud tip GO:0005934
The end of a cellular bud distal to the site of attachment to the mother cell.
7 Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA)
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
7 Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA) Q12518 (/HDA)
Actin cortical patch GO:0030479
An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
1 O74423 (/IDA)
Actin cortical patch GO:0030479
An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
1 G4MSW7 (/ISS)
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