The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-kinase, accessory domain (PIK)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 20: Phosphatidylinositol 4-kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
1-phosphatidylinositol 4-kinase activity GO:0004430
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+).
2 P39104 (/IDA) P39104 (/IDA)
1-phosphatidylinositol 4-kinase activity GO:0004430
Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+).
2 P39104 (/IMP) P39104 (/IMP)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P39104 (/IPI) P39104 (/IPI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
2 P39104 (/IMP) P39104 (/IMP)
Positive regulation of Golgi to plasma membrane protein transport GO:0042998
Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
2 P39104 (/IMP) P39104 (/IMP)
Phosphatidylinositol phosphorylation GO:0046854
The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol.
2 P39104 (/IDA) P39104 (/IDA)
Phosphatidylinositol phosphorylation GO:0046854
The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol.
2 P39104 (/IMP) P39104 (/IMP)
Positive regulation of protein secretion GO:0050714
Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
2 P39104 (/IMP) P39104 (/IMP)
Single-species biofilm formation on inanimate substrate GO:0044011
A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
1 Q9UW24 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 P39104 (/IDA) P39104 (/IDA)
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
2 P39104 (/IDA) P39104 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...