The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Nucleoporin 98-96

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 Q867H5 (/IPI) Q867M2 (/IPI) Q867M7 (/IPI) Q867W7 (/IPI) Q868A8 (/IPI) Q86G43 (/IPI) Q9VCH5 (/IPI)
Structural constituent of nuclear pore GO:0017056
The action of a molecule that contributes to the structural integrity of the nuclear pore complex, a protein-lined channel in the nuclear envelope that allows the transfer of macromolecules.
7 Q867H5 (/ISS) Q867M2 (/ISS) Q867M7 (/ISS) Q867W7 (/ISS) Q868A8 (/ISS) Q86G43 (/ISS) Q9VCH5 (/ISS)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
1 Q9VCH5 (/IDA)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
1 Q9VCH5 (/IMP)
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
1 Q9VCH5 (/IDA)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
7 Q867H5 (/IMP) Q867M2 (/IMP) Q867M7 (/IMP) Q867W7 (/IMP) Q868A8 (/IMP) Q86G43 (/IMP) Q9VCH5 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
7 Q867H5 (/IGI) Q867M2 (/IGI) Q867M7 (/IGI) Q867W7 (/IGI) Q868A8 (/IGI) Q86G43 (/IGI) Q9VCH5 (/IGI)
Germ-line stem cell population maintenance GO:0030718
Any process by which an organism or tissue maintains a population of germ-line stem cells.
7 Q867H5 (/IMP) Q867M2 (/IMP) Q867M7 (/IMP) Q867W7 (/IMP) Q868A8 (/IMP) Q86G43 (/IMP) Q9VCH5 (/IMP)
Larval lymph gland hemopoiesis GO:0035167
The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.
7 Q867H5 (/IMP) Q867M2 (/IMP) Q867M7 (/IMP) Q867W7 (/IMP) Q868A8 (/IMP) Q86G43 (/IMP) Q9VCH5 (/IMP)
Positive regulation of defense response to virus by host GO:0002230
Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.
1 Q9VCH5 (/IMP)
RNA export from nucleus GO:0006405
The directed movement of RNA from the nucleus to the cytoplasm.
1 Q9VCH5 (/IMP)
Positive regulation of actin filament polymerization GO:0030838
Any process that activates or increases the frequency, rate or extent of actin polymerization.
1 Q9VCH5 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q9VCH5 (/IMP)
Response to ecdysone GO:0035075
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.
1 Q9VCH5 (/IDA)
Heat shock-mediated polytene chromosome puffing GO:0035080
The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus.
1 Q9VCH5 (/IDA)
Male germ-line stem cell population maintenance GO:0036098
The process by which an organism or tissue maintains a population of male germ-line stem cells.
1 Q9VCH5 (/IGI)
Negative regulation by host of viral transcription GO:0043922
Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription.
1 Q9VCH5 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q9VCH5 (/IMP)
Regulation of nucleocytoplasmic transport GO:0046822
Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
1 Q9VCH5 (/IMP)
Positive regulation of transcription initiation from RNA polymerase II promoter GO:0060261
Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
1 Q9VCH5 (/IMP)
Cellular response to ecdysone GO:0071390
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.
1 Q9VCH5 (/IDA)
Transcriptional activation by promoter-enhancer looping GO:0071733
The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.
1 Q9VCH5 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
7 Q867H5 (/IPI) Q867M2 (/IPI) Q867M7 (/IPI) Q867W7 (/IPI) Q868A8 (/IPI) Q86G43 (/IPI) Q9VCH5 (/IPI)
Nuclear pore central transport channel GO:0044613
The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153.
7 Q867H5 (/ISS) Q867M2 (/ISS) Q867M7 (/ISS) Q867W7 (/ISS) Q868A8 (/ISS) Q86G43 (/ISS) Q9VCH5 (/ISS)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
1 Q9VCH5 (/IDA)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
1 Q9VCH5 (/IMP)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9VCH5 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9VCH5 (/IMP)
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
1 Q9VCH5 (/IDA)
Polytene chromosome GO:0005700
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
1 Q9VCH5 (/IDA)
Polytene chromosome puff GO:0005703
A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription.
1 Q9VCH5 (/IDA)
Polytene chromosome puff GO:0005703
A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription.
1 Q9VCH5 (/IMP)
Polytene chromosome band GO:0005704
A stretch of densely packed chromatin along the polytene chromosome, visible as a morphologically distinct band.
1 Q9VCH5 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9VCH5 (/IDA)