The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: ubiquitin thioesterase ZRANB1 isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 9 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
8 A0JMQ9 (/ISS) A6QP16 (/ISS) A6QP16 (/ISS) B1H2Q2 (/ISS) Q5U595 (/ISS) Q5U595 (/ISS) Q6NUB7 (/ISS) Q7M760 (/ISS)
Thiol-dependent ubiquitinyl hydrolase activity GO:0036459
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
8 A0JMQ9 (/ISS) A6QP16 (/ISS) A6QP16 (/ISS) B1H2Q2 (/ISS) Q5U595 (/ISS) Q5U595 (/ISS) Q6NUB7 (/ISS) Q7M760 (/ISS)
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
4 Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q9UGI0 (/IPI) Q9UGI0 (/IPI) Q9UGI0 (/IPI) Q9UGI0 (/IPI)
Thiol-dependent ubiquitinyl hydrolase activity GO:0036459
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
4 Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP)
K63-linked polyubiquitin modification-dependent protein binding GO:0070530
Interacting selectively and non-covalently with a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein.
4 Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA)
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
1 Q7M760 (/ISO)
Thiol-dependent ubiquitinyl hydrolase activity GO:0036459
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
1 Q7M760 (/ISO)
K63-linked polyubiquitin modification-dependent protein binding GO:0070530
Interacting selectively and non-covalently with a protein upon poly-ubiquitination formed by linkages between lysine residues at position 63 in the target protein.
1 Q7M760 (/ISO)

There are 27 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
8 A0JMQ9 (/ISS) A6QP16 (/ISS) A6QP16 (/ISS) B1H2Q2 (/ISS) Q5U595 (/ISS) Q5U595 (/ISS) Q6NUB7 (/ISS) Q7M760 (/ISS)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
8 A0JMQ9 (/ISS) A6QP16 (/ISS) A6QP16 (/ISS) B1H2Q2 (/ISS) Q5U595 (/ISS) Q5U595 (/ISS) Q6NUB7 (/ISS) Q7M760 (/ISS)
Regulation of cell morphogenesis GO:0022604
Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.
8 A0JMQ9 (/ISS) A6QP16 (/ISS) A6QP16 (/ISS) B1H2Q2 (/ISS) Q5U595 (/ISS) Q5U595 (/ISS) Q6NUB7 (/ISS) Q7M760 (/ISS)
Positive regulation of Wnt signaling pathway GO:0030177
Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
8 A0JMQ9 (/ISS) A6QP16 (/ISS) A6QP16 (/ISS) B1H2Q2 (/ISS) Q5U595 (/ISS) Q5U595 (/ISS) Q6NUB7 (/ISS) Q7M760 (/ISS)
Protein K29-linked deubiquitination GO:0035523
A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein.
8 A0JMQ9 (/ISS) A6QP16 (/ISS) A6QP16 (/ISS) B1H2Q2 (/ISS) Q5U595 (/ISS) Q5U595 (/ISS) Q6NUB7 (/ISS) Q7M760 (/ISS)
Protein K63-linked deubiquitination GO:0070536
A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.
8 A0JMQ9 (/ISS) A6QP16 (/ISS) A6QP16 (/ISS) B1H2Q2 (/ISS) Q5U595 (/ISS) Q5U595 (/ISS) Q6NUB7 (/ISS) Q7M760 (/ISS)
Protein K33-linked deubiquitination GO:1990168
A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein.
8 A0JMQ9 (/ISS) A6QP16 (/ISS) A6QP16 (/ISS) B1H2Q2 (/ISS) Q5U595 (/ISS) Q5U595 (/ISS) Q6NUB7 (/ISS) Q7M760 (/ISS)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
4 Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
4 A0A2R8RKU1 (/IGI) A0A386INK5 (/IGI) A0JMQ9 (/IGI) E7EYV8 (/IGI)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
4 Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP)
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
4 Q9UGI0 (/TAS) Q9UGI0 (/TAS) Q9UGI0 (/TAS) Q9UGI0 (/TAS)
Regulation of cell morphogenesis GO:0022604
Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.
4 Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP)
Positive regulation of Wnt signaling pathway GO:0030177
Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
4 Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP)
Protein K29-linked deubiquitination GO:0035523
A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein.
4 Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA)
Protein K63-linked deubiquitination GO:0070536
A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.
4 Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA)
Protein K63-linked deubiquitination GO:0070536
A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.
4 Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP)
Protein deubiquitination involved in ubiquitin-dependent protein catabolic process GO:0071947
The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism.
4 Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP) Q9UGI0 (/IMP)
Protein K33-linked deubiquitination GO:1990168
A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein.
4 Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA)
Cytoskeleton organization GO:0007010
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
1 Q7M760 (/ISO)
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
1 Q7M760 (/ISO)
Central nervous system morphogenesis GO:0021551
The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
1 A0JMQ9 (/IMP)
Regulation of cell morphogenesis GO:0022604
Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.
1 Q7M760 (/ISO)
Positive regulation of Wnt signaling pathway GO:0030177
Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
1 Q7M760 (/ISO)
Protein K29-linked deubiquitination GO:0035523
A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein.
1 Q7M760 (/ISO)
Protein K63-linked deubiquitination GO:0070536
A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.
1 Q7M760 (/ISO)
Protein deubiquitination involved in ubiquitin-dependent protein catabolic process GO:0071947
The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism.
1 Q7M760 (/ISO)
Protein K33-linked deubiquitination GO:1990168
A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein.
1 Q7M760 (/ISO)

There are 13 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 A0JMQ9 (/ISS) A6QP16 (/ISS) A6QP16 (/ISS) B1H2Q2 (/ISS) Q5U595 (/ISS) Q5U595 (/ISS) Q6NUB7 (/ISS) Q7M760 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
8 A0JMQ9 (/ISS) A6QP16 (/ISS) A6QP16 (/ISS) B1H2Q2 (/ISS) Q5U595 (/ISS) Q5U595 (/ISS) Q6NUB7 (/ISS) Q7M760 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
4 Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 Q9UGI0 (/TAS) Q9UGI0 (/TAS) Q9UGI0 (/TAS) Q9UGI0 (/TAS)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
4 Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA) Q9UGI0 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q7M760 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q7M760 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q7M760 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q7M760 (/ISO)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 Q7M760 (/ISO)
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