The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
alix/aip1 like domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Bro1p

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 P48582 (/IPI) P48582 (/IPI)
Deubiquitinase activator activity GO:0035800
Increases the activity of deubiquitinase, an enzyme that catalyzes the hydrolysis of various forms of polymeric ubiquitin sequences.
2 P48582 (/IDA) P48582 (/IDA)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ubiquitin-dependent protein catabolic process GO:0006511
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
2 P48582 (/IMP) P48582 (/IMP)
Vacuolar transport GO:0007034
The directed movement of substances into, out of or within a vacuole.
2 P48582 (/IMP) P48582 (/IMP)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
2 P48582 (/IMP) P48582 (/IMP)
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
2 P48582 (/IGI) P48582 (/IGI)
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
2 P48582 (/IPI) P48582 (/IPI)
Protein localization to endosome GO:0036010
A process in which a protein is transported to, or maintained in, a location within an endosome.
2 P48582 (/IMP) P48582 (/IMP)
Protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0043328
The process of directing proteins towards the vacuole that contributes to protein catabolism via the multivesicular body (MVB) pathway.
2 P48582 (/IMP) P48582 (/IMP)
Intralumenal vesicle formation GO:0070676
The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.
2 P48582 (/IGI) P48582 (/IGI)
Intralumenal vesicle formation GO:0070676
The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.
2 P48582 (/IMP) P48582 (/IMP)
Mitochondria-associated ubiquitin-dependent protein catabolic process GO:0072671
The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions.
2 P48582 (/IMP) P48582 (/IMP)
ATP export GO:1904669
The directed movement of ATP out of a cell or organelle.
2 P48582 (/IMP) P48582 (/IMP)
Positive regulation of ubiquitin-specific protease activity GO:2000158
Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.
2 P48582 (/IDA) P48582 (/IDA)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P48582 (/IDA) P48582 (/IDA)
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
2 P48582 (/IDA) P48582 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P48582 (/HDA) P48582 (/HDA)
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