The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Ankyrin repeat-containing domain
".
FunFam 4: Phosphatase 1 regulatory subunit 12A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 16 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | O14974 (/IPI) O60237 (/IPI) Q10728 (/IPI) Q9BZL4 (/IPI) Q9DBR7 (/IPI) |
Phosphatase regulator activity GO:0019208
Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
|
4 | Q10728 (/ISS) Q6DRG7 (/ISS) Q90623 (/ISS) Q9DBR7 (/ISS) |
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
4 | Q10728 (/ISS) Q6DRG7 (/ISS) Q90623 (/ISS) Q9DBR7 (/ISS) |
Enzyme inhibitor activity GO:0004857
Binds to and stops, prevents or reduces the activity of an enzyme.
|
2 | Q10728 (/ISS) Q9DBR7 (/ISS) |
Phosphoprotein phosphatase activity GO:0004721
Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
|
1 | Q10728 (/IDA) |
Enzyme inhibitor activity GO:0004857
Binds to and stops, prevents or reduces the activity of an enzyme.
|
1 | O14974 (/IDA) |
Enzyme inhibitor activity GO:0004857
Binds to and stops, prevents or reduces the activity of an enzyme.
|
1 | Q9DBR7 (/ISO) |
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
|
1 | O60237 (/TAS) |
Phosphatase regulator activity GO:0019208
Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
|
1 | O14974 (/IDA) |
Phosphatase regulator activity GO:0019208
Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
|
1 | O14974 (/IMP) |
Phosphatase regulator activity GO:0019208
Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
|
1 | Q9DBR7 (/ISO) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | O14974 (/IPI) |
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q9DBR7 (/ISO) |
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | Q6DRG7 (/IPI) |
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | O14974 (/IDA) |
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | Q9DBR7 (/ISO) |
There are 50 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
|
13 |
A8JNT4 (/IMP)
A8JNT5 (/IMP)
M9NDA1 (/IMP)
M9NDS8 (/IMP)
M9NEB2 (/IMP)
M9NFF6 (/IMP)
M9PCQ3 (/IMP)
Q86R99 (/IMP)
Q86RA0 (/IMP)
Q8IQN4 (/IMP)
(3 more) |
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
|
13 |
A8JNT4 (/NAS)
A8JNT5 (/NAS)
M9NDA1 (/NAS)
M9NDS8 (/NAS)
M9NEB2 (/NAS)
M9NFF6 (/NAS)
M9PCQ3 (/NAS)
Q86R99 (/NAS)
Q86RA0 (/NAS)
Q8IQN4 (/NAS)
(3 more) |
Imaginal disc morphogenesis GO:0007560
The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
|
13 |
A8JNT4 (/IMP)
A8JNT5 (/IMP)
M9NDA1 (/IMP)
M9NDS8 (/IMP)
M9NEB2 (/IMP)
M9NFF6 (/IMP)
M9PCQ3 (/IMP)
Q86R99 (/IMP)
Q86RA0 (/IMP)
Q8IQN4 (/IMP)
(3 more) |
Epidermis development GO:0008544
The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.
|
13 |
A8JNT4 (/IMP)
A8JNT5 (/IMP)
M9NDA1 (/IMP)
M9NDS8 (/IMP)
M9NEB2 (/IMP)
M9NFF6 (/IMP)
M9PCQ3 (/IMP)
Q86R99 (/IMP)
Q86RA0 (/IMP)
Q8IQN4 (/IMP)
(3 more) |
Germline ring canal formation GO:0030725
Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts.
|
13 |
A8JNT4 (/IMP)
A8JNT5 (/IMP)
M9NDA1 (/IMP)
M9NDS8 (/IMP)
M9NEB2 (/IMP)
M9NFF6 (/IMP)
M9PCQ3 (/IMP)
Q86R99 (/IMP)
Q86RA0 (/IMP)
Q8IQN4 (/IMP)
(3 more) |
Imaginal disc-derived wing hair organization GO:0035317
A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.
|
13 |
A8JNT4 (/IMP)
A8JNT5 (/IMP)
M9NDA1 (/IMP)
M9NDS8 (/IMP)
M9NEB2 (/IMP)
M9NFF6 (/IMP)
M9PCQ3 (/IMP)
Q86R99 (/IMP)
Q86RA0 (/IMP)
Q8IQN4 (/IMP)
(3 more) |
Regulation of compound eye photoreceptor development GO:0045314
Any process that modulates the frequency, rate or extent of compound eye photoreceptor development.
|
13 |
A8JNT4 (/IMP)
A8JNT5 (/IMP)
M9NDA1 (/IMP)
M9NDS8 (/IMP)
M9NEB2 (/IMP)
M9NFF6 (/IMP)
M9PCQ3 (/IMP)
Q86R99 (/IMP)
Q86RA0 (/IMP)
Q8IQN4 (/IMP)
(3 more) |
Axon extension GO:0048675
Long distance growth of a single axon process involved in cellular development.
|
13 |
A8JNT4 (/IMP)
A8JNT5 (/IMP)
M9NDA1 (/IMP)
M9NDS8 (/IMP)
M9NEB2 (/IMP)
M9NFF6 (/IMP)
M9PCQ3 (/IMP)
Q86R99 (/IMP)
Q86RA0 (/IMP)
Q8IQN4 (/IMP)
(3 more) |
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
|
13 |
A8JNT4 (/IMP)
A8JNT5 (/IMP)
M9NDA1 (/IMP)
M9NDS8 (/IMP)
M9NEB2 (/IMP)
M9NFF6 (/IMP)
M9PCQ3 (/IMP)
Q86R99 (/IMP)
Q86RA0 (/IMP)
Q8IQN4 (/IMP)
(3 more) |
Regulation of locomotor rhythm GO:1904059
Any process that modulates the frequency, rate or extent of locomotor rhythm.
|
13 |
A8JNT4 (/IMP)
A8JNT5 (/IMP)
M9NDA1 (/IMP)
M9NDS8 (/IMP)
M9NEB2 (/IMP)
M9NFF6 (/IMP)
M9PCQ3 (/IMP)
Q86R99 (/IMP)
Q86RA0 (/IMP)
Q8IQN4 (/IMP)
(3 more) |
Embryo development ending in birth or egg hatching GO:0009792
The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
|
4 | G5ECD7 (/IMP) G5EEB3 (/IMP) G5EG29 (/IMP) G5EGT0 (/IMP) |
Embryonic body morphogenesis GO:0010172
The process in which the anatomical structures of the embryonic soma are generated and organized.
|
4 | G5ECD7 (/IMP) G5EEB3 (/IMP) G5EG29 (/IMP) G5EGT0 (/IMP) |
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
|
4 | Q10728 (/ISS) Q6DRG7 (/ISS) Q90623 (/ISS) Q9DBR7 (/ISS) |
Regulation of myosin-light-chain-phosphatase activity GO:0035507
Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity.
|
4 | Q10728 (/ISS) Q6DRG7 (/ISS) Q90623 (/ISS) Q9DBR7 (/ISS) |
Embryonic morphogenesis GO:0048598
The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.
|
4 | G5ECD7 (/IGI) G5EEB3 (/IGI) G5EG29 (/IGI) G5EGT0 (/IGI) |
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
|
2 | O14974 (/TAS) O60237 (/TAS) |
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
2 | Q10728 (/ISS) Q9DBR7 (/ISS) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
2 | O14974 (/IMP) Q9DBR7 (/IMP) |
Centrosome cycle GO:0007098
The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
|
2 | Q10728 (/ISS) Q9DBR7 (/ISS) |
Cellular response to insulin stimulus GO:0032869
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
|
2 | E1BC59 (/IDA) E1BC59 (/IDA) |
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
|
2 | Q10728 (/ISS) Q9DBR7 (/ISS) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | Q10728 (/ISS) Q9DBR7 (/ISS) |
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
1 | O14974 (/IMP) |
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
1 | Q9DBR7 (/ISO) |
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
|
1 | Q6DRG7 (/IMP) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
1 | Q9DBR7 (/ISO) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
1 | Q10728 (/ISS) |
Regulation of muscle contraction GO:0006937
Any process that modulates the frequency, rate or extent of muscle contraction.
|
1 | O60237 (/TAS) |
Centrosome cycle GO:0007098
The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
|
1 | O14974 (/IMP) |
Centrosome cycle GO:0007098
The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
|
1 | Q9DBR7 (/ISO) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
1 | O60237 (/TAS) |
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
|
1 | Q6DRG7 (/IMP) |
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | Q6DRG7 (/IMP) |
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
|
1 | Q6DRG7 (/IMP) |
Midbrain-hindbrain boundary morphogenesis GO:0021555
The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
|
1 | Q6DRG7 (/IMP) |
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
|
1 | O14974 (/IDA) |
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
|
1 | Q9DBR7 (/ISO) |
Regulation of myosin-light-chain-phosphatase activity GO:0035507
Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity.
|
1 | O14974 (/IDA) |
Regulation of myosin-light-chain-phosphatase activity GO:0035507
Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity.
|
1 | Q9DBR7 (/ISO) |
Positive regulation of myosin-light-chain-phosphatase activity GO:0035508
Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity.
|
1 | O14974 (/IMP) |
Positive regulation of myosin-light-chain-phosphatase activity GO:0035508
Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity.
|
1 | Q9DBR7 (/ISO) |
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | Q9DBR7 (/IDA) |
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
|
1 | O14974 (/IDA) |
Negative regulation of catalytic activity GO:0043086
Any process that stops or reduces the activity of an enzyme.
|
1 | Q9DBR7 (/ISO) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O14974 (/IDA) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q9DBR7 (/ISO) |
Regulation of nucleocytoplasmic transport GO:0046822
Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
|
1 | Q9DBR7 (/IMP) |
Actin filament bundle assembly GO:0051017
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
|
1 | Q6DRG7 (/IMP) |
Convergent extension involved in axis elongation GO:0060028
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism.
|
1 | Q6DRG7 (/IGI) |
Actin filament bundle distribution GO:0070650
Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell.
|
1 | Q6DRG7 (/IMP) |
There are 26 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Apical part of cell GO:0045177
The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
|
13 |
A8JNT4 (/IDA)
A8JNT5 (/IDA)
M9NDA1 (/IDA)
M9NDS8 (/IDA)
M9NEB2 (/IDA)
M9NFF6 (/IDA)
M9PCQ3 (/IDA)
Q86R99 (/IDA)
Q86RA0 (/IDA)
Q8IQN4 (/IDA)
(3 more) |
Apical cortex GO:0045179
The region that lies just beneath the plasma membrane on the apical edge of a cell.
|
13 |
A8JNT4 (/IDA)
A8JNT5 (/IDA)
M9NDA1 (/IDA)
M9NDS8 (/IDA)
M9NEB2 (/IDA)
M9NFF6 (/IDA)
M9PCQ3 (/IDA)
Q86R99 (/IDA)
Q86RA0 (/IDA)
Q8IQN4 (/IDA)
(3 more) |
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
|
5 | O14974 (/ISS) O60237 (/ISS) Q10728 (/ISS) Q6DRG7 (/ISS) Q90623 (/ISS) |
A band GO:0031672
The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
|
5 | O14974 (/ISS) O60237 (/ISS) Q10728 (/ISS) Q6DRG7 (/ISS) Q90623 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | G5ECD7 (/IDA) G5EEB3 (/IDA) G5EG29 (/IDA) G5EGT0 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | O14974 (/TAS) O60237 (/TAS) Q10728 (/TAS) Q8IQN4 (/TAS) |
Cell-cell adherens junction GO:0005913
An adherens junction which connects a cell to another cell.
|
4 | G5ECD7 (/IDA) G5EEB3 (/IDA) G5EG29 (/IDA) G5EGT0 (/IDA) |
PTW/PP1 phosphatase complex GO:0072357
A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
|
4 | Q10728 (/ISS) Q6DRG7 (/ISS) Q90623 (/ISS) Q9DBR7 (/ISS) |
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
2 | Q10728 (/ISS) Q9DBR7 (/ISS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
2 | O14974 (/TAS) O60237 (/TAS) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
2 | Q10728 (/ISS) Q9DBR7 (/ISS) |
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
|
2 | Q8BG95 (/IDA) Q9DBR7 (/IDA) |
A band GO:0031672
The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
|
2 | Q8BG95 (/IDA) Q9DBR7 (/IDA) |
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
1 | O14974 (/IDA) |
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
|
1 | Q9DBR7 (/ISO) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
1 | O14974 (/IDA) |
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
|
1 | Q9DBR7 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O14974 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9DBR7 (/ISO) |
Focal adhesion GO:0005925
Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
|
1 | O14974 (/HDA) |
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
1 | O14974 (/IDA) |
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
1 | Q9DBR7 (/ISO) |
Contractile fiber GO:0043292
Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
|
1 | O14974 (/IDA) |
Contractile fiber GO:0043292
Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
|
1 | Q9DBR7 (/ISO) |
PTW/PP1 phosphatase complex GO:0072357
A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
|
1 | O14974 (/IDA) |
PTW/PP1 phosphatase complex GO:0072357
A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
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1 | Q9DBR7 (/ISO) |