The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Protein prenylyltransferase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Protein farnesyltransferase/geranylgeranyltransfer...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein farnesyltransferase activity GO:0004660
Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.
4 O24304 (/ISS) P93227 (/ISS) Q9LX33 (/ISS) Q9LX33 (/ISS)
Protein geranylgeranyltransferase activity GO:0004661
Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein.
4 O24304 (/ISS) P93227 (/ISS) Q9LX33 (/ISS) Q9LX33 (/ISS)
Farnesyltranstransferase activity GO:0004311
Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
2 Q9LX33 (/TAS) Q9LX33 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q9LX33 (/IPI) Q9LX33 (/IPI)
Protein prenyltransferase activity GO:0008318
Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein.
2 Q9LX33 (/IDA) Q9LX33 (/IDA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein farnesylation GO:0018343
The covalent attachment of a farnesyl group to a protein.
4 O24304 (/ISS) P93227 (/ISS) Q9LX33 (/ISS) Q9LX33 (/ISS)
Regulation of cell shape GO:0008360
Any process that modulates the surface configuration of a cell.
2 Q9LX33 (/IMP) Q9LX33 (/IMP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
2 Q9LX33 (/IMP) Q9LX33 (/IMP)
Negative regulation of abscisic acid-activated signaling pathway GO:0009788
Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.
2 Q9LX33 (/IMP) Q9LX33 (/IMP)
Protein prenylation GO:0018342
The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.
2 Q9LX33 (/IDA) Q9LX33 (/IDA)
Protein farnesylation GO:0018343
The covalent attachment of a farnesyl group to a protein.
2 Q9LX33 (/TAS) Q9LX33 (/TAS)
Protein geranylgeranylation GO:0018344
The covalent attachment of a geranylgeranyl group to a protein.
2 Q9LX33 (/IDA) Q9LX33 (/IDA)
Protein geranylgeranylation GO:0018344
The covalent attachment of a geranylgeranyl group to a protein.
2 O24304 (/ISS) P93227 (/ISS)
Regulation of meristem development GO:0048509
Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.
2 Q9LX33 (/IMP) Q9LX33 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
CAAX-protein geranylgeranyltransferase complex GO:0005953
A heterodimeric enzyme, composed of an alpha and a beta subunit. Participates in the post-translational C-terminal modification of several small GTPases, allowing their targeting to the membrane.
2 O24304 (/ISS) P93227 (/ISS)
Protein farnesyltransferase complex GO:0005965
A protein complex that possesses protein farnesyltransferase activity.
2 O24304 (/ISS) P93227 (/ISS)
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