The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Leucine-rich Repeat Variant
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 469: Crm1p

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P30822 (/IPI) P30822 (/IPI) P30822 (/IPI) P30822 (/IPI)
Nuclear import signal receptor activity GO:0061608
Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
4 P30822 (/IDA) P30822 (/IDA) P30822 (/IDA) P30822 (/IDA)
Nuclear import signal receptor activity GO:0061608
Combining with a nuclear import signal (NIS) on a cargo to be transported, to mediate transport of the cargo through the nuclear pore, from the cytoplasm to the nuclear lumen. The cargo can be either a RNA or a protein.
4 P30822 (/IMP) P30822 (/IMP) P30822 (/IMP) P30822 (/IMP)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ribosomal large subunit export from nucleus GO:0000055
The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.
4 P30822 (/IMP) P30822 (/IMP) P30822 (/IMP) P30822 (/IMP)
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
4 P30822 (/IMP) P30822 (/IMP) P30822 (/IMP) P30822 (/IMP)
Protein export from nucleus GO:0006611
The directed movement of a protein from the nucleus into the cytoplasm.
4 P30822 (/IMP) P30822 (/IMP) P30822 (/IMP) P30822 (/IMP)
Protein localization to kinetochore GO:0034501
Any process in which a protein is transported to, or maintained at, the kinetochore.
4 P30822 (/IGI) P30822 (/IGI) P30822 (/IGI) P30822 (/IGI)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
4 P30822 (/IDA) P30822 (/IDA) P30822 (/IDA) P30822 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 P30822 (/IDA) P30822 (/IDA) P30822 (/IDA) P30822 (/IDA)
Spindle pole body GO:0005816
The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
4 P30822 (/IDA) P30822 (/IDA) P30822 (/IDA) P30822 (/IDA)
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