The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Bromodomain-like
".
FunFam 47: Bromodomain-containing factor 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lysine-acetylated histone binding GO:0070577
Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
|
5 | P35817 (/IDA) P35817 (/IDA) Q07442 (/IDA) Q07442 (/IDA) Q5A4W8 (/IDA) |
|
Core promoter binding GO:0001047
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
4 | P35817 (/IDA) P35817 (/IDA) Q07442 (/IDA) Q07442 (/IDA) |
|
TFIID-class transcription factor complex binding GO:0001094
Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
|
4 | P35817 (/IPI) P35817 (/IPI) Q07442 (/IPI) Q07442 (/IPI) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | P35817 (/IPI) P35817 (/IPI) Q07442 (/IPI) Q07442 (/IPI) |
|
TFIID-class transcription factor complex binding GO:0001094
Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
|
2 | P35817 (/IDA) P35817 (/IDA) |
|
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
2 | P35817 (/IDA) P35817 (/IDA) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
2 | Q07442 (/IDA) Q07442 (/IDA) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of heterochromatin assembly GO:0031452
Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation.
|
4 | P35817 (/IGI) P35817 (/IGI) Q07442 (/IGI) Q07442 (/IGI) |
|
Negative regulation of heterochromatin assembly GO:0031452
Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation.
|
4 | P35817 (/IMP) P35817 (/IMP) Q07442 (/IMP) Q07442 (/IMP) |
|
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
|
2 | P35817 (/IMP) P35817 (/IMP) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
2 | P35817 (/IPI) P35817 (/IPI) |
|
SnRNA transcription GO:0009301
The synthesis of small nuclear RNA (snRNA) from a DNA template.
|
2 | P35817 (/IMP) P35817 (/IMP) |
|
Regulation of chromatin silencing at telomere GO:0031938
Any process that affects the rate, extent or location of chromatin silencing at telomeres.
|
2 | P35817 (/IMP) P35817 (/IMP) |
|
Regulation of chromatin silencing at silent mating-type cassette GO:0090054
Any process that modulates the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.
|
2 | P35817 (/IMP) P35817 (/IMP) |
|
Positive regulation of histone exchange GO:1900051
Any process that activates or increases the frequency, rate or extent of histone exchange.
|
2 | P35817 (/IMP) P35817 (/IMP) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
2 | P35817 (/IDA) P35817 (/IDA) |
|
Swr1 complex GO:0000812
A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.
|
2 | P35817 (/IDA) P35817 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | Q07442 (/IC) Q07442 (/IC) |
|
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
|
2 | Q07442 (/HDA) Q07442 (/HDA) |
