The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors.

Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.

Repression of transcription of ribosomal DNA by altering the structure of chromatin.

The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.

The modification of histones by removal of acetyl groups.

Repression of transcription of ribosomal DNA by altering the structure of chromatin.

Repression of transcription of ribosomal DNA by altering the structure of chromatin.

The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.

Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.

Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.

Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.

The cellular synthesis of RNA on a template of DNA.

Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase I.

The modification of histones by removal of acetyl groups.

The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone.

The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.

Any process that results in the assembly of chromatin into heterochromatin and contributes to chromatin silencing.

Any process that results in the assembly of chromatin into heterochromatin and contributes to chromatin silencing.

The modification of histone H4 by the removal of one or more acetyl groups.

Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.

Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

A region of heterochromatin located at the rDNA repeats in a chromosome.

That part of the nuclear content other than the chromosomes or the nucleolus.

Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.

A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.

A region of heterochromatin located at the rDNA repeats in a chromosome.