The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: ropporin-1-like protein isoform X2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 Q96C74 (/IPI) Q9BZX4 (/IPI) Q9BZX4 (/IPI) Q9EQ00 (/IPI) Q9ESG2 (/IPI) Q9HAT0 (/IPI) Q9HAT0 (/IPI)
Receptor signaling complex adaptor activity GO:0030159
Functions to provide a physical support for the assembly of a multiprotein receptor signaling complex.
2 Q9BZX4 (/NAS) Q9BZX4 (/NAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 Q9HAT0 (/IPI) Q9HAT0 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q9BZX4 (/NAS) Q9BZX4 (/NAS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
2 Q9BZX4 (/IPI) Q9BZX4 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q9ESG2 (/ISO)

There are 20 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
11 Q3T024 (/ISS) Q3T064 (/ISS) Q4KLL5 (/ISS) Q4R6C5 (/ISS) Q4R6C5 (/ISS) Q4R760 (/ISS) Q96C74 (/ISS) Q9BZX4 (/ISS) Q9BZX4 (/ISS) Q9HAT0 (/ISS)
(1 more)
Flagellated sperm motility GO:0030317
Any process involved in the controlled movement of a flagellated sperm cell.
11 Q3T024 (/ISS) Q3T064 (/ISS) Q4KLL5 (/ISS) Q4R6C5 (/ISS) Q4R6C5 (/ISS) Q4R760 (/ISS) Q96C74 (/ISS) Q9BZX4 (/ISS) Q9BZX4 (/ISS) Q9HAT0 (/ISS)
(1 more)
Sperm capacitation GO:0048240
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
11 Q3T024 (/ISS) Q3T064 (/ISS) Q4KLL5 (/ISS) Q4R6C5 (/ISS) Q4R6C5 (/ISS) Q4R760 (/ISS) Q96C74 (/ISS) Q9BZX4 (/ISS) Q9BZX4 (/ISS) Q9HAT0 (/ISS)
(1 more)
Cilium organization GO:0044782
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
8 Q3T064 (/ISS) Q4KLL5 (/ISS) Q4R6C5 (/ISS) Q4R6C5 (/ISS) Q9BZX4 (/ISS) Q9BZX4 (/ISS) Q9HAT0 (/ISS) Q9HAT0 (/ISS)
Protein localization to cilium GO:0061512
A process in which a protein is transported to, or maintained in, a location within a cilium.
8 Q3T064 (/ISS) Q4KLL5 (/ISS) Q4R6C5 (/ISS) Q4R6C5 (/ISS) Q9BZX4 (/ISS) Q9BZX4 (/ISS) Q9HAT0 (/ISS) Q9HAT0 (/ISS)
Regulation of protein phosphorylation GO:0001932
Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
2 Q9EQ00 (/IMP) Q9ESG2 (/IMP)
Rho protein signal transduction GO:0007266
A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
2 Q9BZX4 (/TAS) Q9BZX4 (/TAS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
2 Q9BZX4 (/NAS) Q9BZX4 (/NAS)
Spermatid development GO:0007286
The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
2 Q66IC9 (/IMP) Q66IC9 (/IMP)
Acrosome reaction GO:0007340
The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida of the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the zona pellucida.
2 Q9BZX4 (/NAS) Q9BZX4 (/NAS)
Fusion of sperm to egg plasma membrane involved in single fertilization GO:0007342
The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.
2 Q9BZX4 (/NAS) Q9BZX4 (/NAS)
Flagellated sperm motility GO:0030317
Any process involved in the controlled movement of a flagellated sperm cell.
2 Q9EQ00 (/IMP) Q9ESG2 (/IMP)
Flagellated sperm motility GO:0030317
Any process involved in the controlled movement of a flagellated sperm cell.
2 Q9BZX4 (/TAS) Q9BZX4 (/TAS)
Sperm capacitation GO:0048240
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
2 Q9EQ00 (/IMP) Q9ESG2 (/IMP)
Cytoskeleton-dependent cytokinesis GO:0061640
A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton.
2 Q9BZX4 (/NAS) Q9BZX4 (/NAS)
Cell-cell adhesion GO:0098609
The attachment of one cell to another cell via adhesion molecules.
2 Q9BZX4 (/NAS) Q9BZX4 (/NAS)
Cilium movement GO:0003341
The directed, self-propelled movement of a cilium.
1 Q9EQ00 (/IMP)
Epithelial cilium movement involved in extracellular fluid movement GO:0003351
The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid.
1 Q96C74 (/IC)
Cilium organization GO:0044782
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
1 Q9ESG2 (/IGI)
Protein localization to cilium GO:0061512
A process in which a protein is transported to, or maintained in, a location within a cilium.
1 Q9ESG2 (/IGI)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
6 Q96C74 (/IDA) Q9BZX4 (/IDA) Q9BZX4 (/IDA) Q9ESG2 (/IDA) Q9HAT0 (/IDA) Q9HAT0 (/IDA)
Motile cilium GO:0031514
A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.
4 Q96C74 (/IDA) Q9BZX4 (/IDA) Q9BZX4 (/IDA) Q9EQ00 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q9HAT0 (/HDA) Q9HAT0 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 Q9EQ00 (/ISO) Q9ESG2 (/ISO)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
2 Q38DT2 (/IDA) Q38DT2 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9ESG2 (/TAS)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
1 Q96C74 (/IDA)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
1 Q9EQ00 (/ISO)
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
1 E9AFN2 (/ISO)
Motile cilium GO:0031514
A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.
1 Q9EQ00 (/ISO)
Sperm principal piece GO:0097228
The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece.
1 Q9ESG2 (/IDA)
Sperm cytoplasmic droplet GO:0097598
A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce \residual bodies\. Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from \excessive residual cytoplasm\ that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted.
1 Q9ESG2 (/IDA)
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