CATH Superfamily 1.20.58.60
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 135: Spectrin beta chain, non-erythrocytic
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 11 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
7 | A8JNJ6 (/IDA) M9PBL6 (/IDA) Q23980 (/IDA) Q7KV69 (/IDA) Q7KV70 (/IDA) Q8MRH2 (/IDA) Q9VZQ3 (/IDA) |
|
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
7 | A8JNJ6 (/ISS) M9PBL6 (/ISS) Q23980 (/ISS) Q7KV69 (/ISS) Q7KV70 (/ISS) Q8MRH2 (/ISS) Q9VZQ3 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | A8JNJ6 (/IPI) M9PBL6 (/IPI) Q23980 (/IPI) Q7KV69 (/IPI) Q7KV70 (/IPI) Q8MRH2 (/IPI) Q9VZQ3 (/IPI) |
|
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
|
7 | A8JNJ6 (/IDA) M9PBL6 (/IDA) Q23980 (/IDA) Q7KV69 (/IDA) Q7KV70 (/IDA) Q8MRH2 (/IDA) Q9VZQ3 (/IDA) |
|
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
1 | Q9NRC6 (/NAS) |
|
Kinesin binding GO:0019894
Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.
|
1 | Q9NRC6 (/IDA) |
|
Spectrin binding GO:0030507
Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.
|
1 | Q9NRC6 (/IDA) |
|
Myosin tail binding GO:0032029
Interacting selectively and non-covalently with the tail region of a myosin heavy chain.
|
1 | Q9NRC6 (/IDA) |
|
Dynactin binding GO:0034452
Interacting selectively and non-covalently with any part of a dynactin complex; dynactin is a large protein complex that activates dynein-based motor activity.
|
1 | Q9NRC6 (/IDA) |
|
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
1 | Q9NRC6 (/IDA) |
|
Dynein intermediate chain binding GO:0045505
Interacting selectively and non-covalently with an intermediate chain of the dynein complex.
|
1 | Q9NRC6 (/IDA) |
There are 14 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
|
7 | A8JNJ6 (/IMP) M9PBL6 (/IMP) Q23980 (/IMP) Q7KV69 (/IMP) Q7KV70 (/IMP) Q8MRH2 (/IMP) Q9VZQ3 (/IMP) |
|
Plasma membrane organization GO:0007009
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.
|
7 | A8JNJ6 (/TAS) M9PBL6 (/TAS) Q23980 (/TAS) Q7KV69 (/TAS) Q7KV70 (/TAS) Q8MRH2 (/TAS) Q9VZQ3 (/TAS) |
|
Regulation of multivesicular body size involved in endosome transport GO:0010797
Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles.
|
7 | A8JNJ6 (/IMP) M9PBL6 (/IMP) Q23980 (/IMP) Q7KV69 (/IMP) Q7KV70 (/IMP) Q8MRH2 (/IMP) Q9VZQ3 (/IMP) |
|
Ovarian follicle cell development GO:0030707
The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.
|
7 | A8JNJ6 (/TAS) M9PBL6 (/TAS) Q23980 (/TAS) Q7KV69 (/TAS) Q7KV70 (/TAS) Q8MRH2 (/TAS) Q9VZQ3 (/TAS) |
|
Endosome transport via multivesicular body sorting pathway GO:0032509
The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.
|
7 | A8JNJ6 (/IMP) M9PBL6 (/IMP) Q23980 (/IMP) Q7KV69 (/IMP) Q7KV70 (/IMP) Q8MRH2 (/IMP) Q9VZQ3 (/IMP) |
|
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
|
7 | A8JNJ6 (/IMP) M9PBL6 (/IMP) Q23980 (/IMP) Q7KV69 (/IMP) Q7KV70 (/IMP) Q8MRH2 (/IMP) Q9VZQ3 (/IMP) |
|
Zonula adherens assembly GO:0045186
Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
|
7 | A8JNJ6 (/TAS) M9PBL6 (/TAS) Q23980 (/TAS) Q7KV69 (/TAS) Q7KV70 (/TAS) Q8MRH2 (/TAS) Q9VZQ3 (/TAS) |
|
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.
|
1 | Q9NRC6 (/TAS) |
|
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
1 | Q9NRC6 (/TAS) |
|
Golgi organization GO:0007030
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
|
1 | Q9NRC6 (/IMP) |
|
Lysosomal transport GO:0007041
The directed movement of substances into, out of or within a lysosome.
|
1 | Q9NRC6 (/IMP) |
|
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
|
1 | Q9NRC6 (/TAS) |
|
Actin cytoskeleton organization GO:0030036
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
|
1 | Q9NRC6 (/NAS) |
|
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | Q9NRC6 (/IDA) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | A8JNJ6 (/HDA) M9PBL6 (/HDA) Q23980 (/HDA) Q7KV69 (/HDA) Q7KV70 (/HDA) Q8MRH2 (/HDA) Q9VZQ3 (/HDA) |
|
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
|
7 | A8JNJ6 (/IDA) M9PBL6 (/IDA) Q23980 (/IDA) Q7KV69 (/IDA) Q7KV70 (/IDA) Q8MRH2 (/IDA) Q9VZQ3 (/IDA) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
7 | A8JNJ6 (/IDA) M9PBL6 (/IDA) Q23980 (/IDA) Q7KV69 (/IDA) Q7KV70 (/IDA) Q8MRH2 (/IDA) Q9VZQ3 (/IDA) |
|
Apicolateral plasma membrane GO:0016327
The apical end of the lateral plasma membrane of epithelial cells.
|
7 | A8JNJ6 (/TAS) M9PBL6 (/TAS) Q23980 (/TAS) Q7KV69 (/TAS) Q7KV70 (/TAS) Q8MRH2 (/TAS) Q9VZQ3 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9NRC6 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9NRC6 (/TAS) |
|
Axoneme GO:0005930
The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
|
1 | F7HAE6 (/IDA) |
|
Spectrin GO:0008091
Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins.
|
1 | Q9NRC6 (/NAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9NRC6 (/NAS) |
|
Photoreceptor connecting cilium GO:0032391
The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
|
1 | Q9NRC6 (/IDA) |
|
Photoreceptor disc membrane GO:0097381
Stack of disc membranes located inside a photoreceptor outer segment, and containing densely packed molecules of photoreceptor proteins that traverse the lipid bilayer. Disc membranes arise as evaginations of the ciliary membrane during the development of the outer segment and may or may not remain contiguous with the ciliary membrane.
|
1 | Q9NRC6 (/IDA) |
