The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Neurotransmitter-gated ion-channel transmembrane domain
".
FunFam 76: Glutamate-gated chloride channel, putative
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Excitatory extracellular ligand-gated ion channel activity GO:0005231
Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential.
|
1 | G5ECJ0 (/IDA) |
|
GABA receptor activity GO:0016917
Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms.
|
1 | G5ECJ0 (/IDA) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | G5ECJ0 (/IDA) |
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | G5ECJ0 (/IDA) |
|
Lipid transport involved in lipid storage GO:0010877
The directed movement of lipids into cells that is part of their accumulation and maintenance.
|
1 | G5ECJ0 (/IMP) |
|
Defecation GO:0030421
The expulsion of feces from the rectum.
|
1 | G5ECJ0 (/IMP) |
|
Positive regulation of muscle contraction GO:0045933
Any process that activates or increases the frequency, rate or extent of muscle contraction.
|
1 | G5ECJ0 (/IMP) |
|
Positive regulation of intestinal lipid absorption GO:1904731
Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption.
|
1 | G5ECJ0 (/IMP) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
|
1 | G5ECJ0 (/IDA) |
