The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Neurotransmitter-gated ion-channel transmembrane domain
".
FunFam 50: glycine receptor subunit alpha-4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glycine-gated chloride ion channel activity GO:0022852
Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.
|
1 | Q9VVH4 (/TAS) |
|
PH-gated chloride channel activity GO:0061797
A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH.
|
1 | Q9V9Y4 (/IDA) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
|
1 | Q9VVH4 (/IGI) |
|
Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
|
1 | Q9VVH4 (/IMP) |
|
Synaptic transmission, glycinergic GO:0060012
The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
|
1 | Q9VVH4 (/IGI) |
|
Chloride transmembrane transport GO:1902476
The process in which chloride is transported across a membrane.
|
1 | Q9V9Y4 (/IDA) |
|
Negative regulation of neuronal action potential GO:1904456
Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential.
|
1 | Q9VVH4 (/IMP) |
|
Regulation of renal water transport GO:2001151
Any process that modulates the frequency, rate or extent of renal water transport.
|
1 | Q9V9Y4 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | Q9V9Y4 (/IDA) |
|
Transmembrane transporter complex GO:1902495
A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.
|
1 | Q9V9Y4 (/IDA) |