The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Neurotransmitter-gated ion-channel transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 21: glutamate-gated chloride channel isoform X12

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
PH-gated chloride channel activity GO:0061797
A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH.
18 E1JI08 (/IDA) M9NEB0 (/IDA) M9NFY2 (/IDA) M9PCN0 (/IDA) M9PCN5 (/IDA) M9PFD4 (/IDA) M9PFD7 (/IDA) M9PFL8 (/IDA) M9PFR7 (/IDA) M9PI70 (/IDA)
(8 more)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chloride transmembrane transport GO:1902476
The process in which chloride is transported across a membrane.
18 E1JI08 (/IDA) M9NEB0 (/IDA) M9NFY2 (/IDA) M9PCN0 (/IDA) M9PCN5 (/IDA) M9PFD4 (/IDA) M9PFD7 (/IDA) M9PFL8 (/IDA) M9PFR7 (/IDA) M9PI70 (/IDA)
(8 more)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 M9PI70 (/IDA)
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