The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Neurotransmitter-gated ion-channel transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Neuronal nicotinic acetylcholine receptor subunit ...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 27 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
14 O70174 (/IPI) O70174 (/IPI) P09481 (/IPI) P09482 (/IPI) P09483 (/IPI) P20420 (/IPI) P26152 (/IPI) P30532 (/IPI) P32297 (/IPI) P43681 (/IPI)
(4 more)
Acetylcholine-gated cation-selective channel activity GO:0022848
Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
10 O70174 (/TAS) O70174 (/TAS) P30532 (/TAS) P32297 (/TAS) P43681 (/TAS) Q05901 (/TAS) Q05901 (/TAS) Q05901 (/TAS) Q15825 (/TAS) Q15825 (/TAS)
Acetylcholine-gated cation-selective channel activity GO:0022848
Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
8 P18845 (/ISS) P32297 (/ISS) Q07263 (/ISS) Q19AE6 (/ISS) Q5IS76 (/ISS) Q5IS76 (/ISS) Q5IS77 (/ISS) Q5IS77 (/ISS)
Acetylcholine receptor activity GO:0015464
Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
7 P18845 (/ISS) Q07263 (/ISS) Q19AE6 (/ISS) Q5IS76 (/ISS) Q5IS76 (/ISS) Q5IS77 (/ISS) Q5IS77 (/ISS)
Acetylcholine-gated cation-selective channel activity GO:0022848
Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
7 O70174 (/IMP) O70174 (/IMP) P04757 (/IMP) P09483 (/IMP) P20420 (/IMP) Q8R4G9 (/IMP) Q9R0W9 (/IMP)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
6 O70174 (/ISO) O70174 (/ISO) Q8BMN3 (/ISO) Q8R4G9 (/ISO) Q91X60 (/ISO) Q9R0W9 (/ISO)
Acetylcholine binding GO:0042166
Interacting selectively and non-covalently with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.
6 O70174 (/ISO) O70174 (/ISO) Q2MKA5 (/ISO) Q8BMN3 (/ISO) Q8R4G9 (/ISO) Q91X60 (/ISO)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
5 P04757 (/IDA) P09483 (/IDA) P12389 (/IDA) P12391 (/IDA) P43143 (/IDA)
Acetylcholine receptor activity GO:0015464
Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
5 P04757 (/IDA) P30532 (/IDA) P32297 (/IDA) P43681 (/IDA) Q15822 (/IDA)
Acetylcholine receptor activity GO:0015464
Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
5 O70174 (/ISO) O70174 (/ISO) Q2MKA5 (/ISO) Q8R4G9 (/ISO) Q91X60 (/ISO)
Acetylcholine-gated cation-selective channel activity GO:0022848
Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
5 P09483 (/IDA) P12389 (/IDA) P32297 (/IDA) P43681 (/IDA) Q15822 (/IDA)
Acetylcholine-gated cation-selective channel activity GO:0022848
Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
5 O70174 (/ISO) O70174 (/ISO) Q2MKA5 (/ISO) Q8R4G9 (/ISO) Q91X60 (/ISO)
Acetylcholine binding GO:0042166
Interacting selectively and non-covalently with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.
5 P04757 (/IDA) P09483 (/IDA) P12389 (/IDA) P12391 (/IDA) P20420 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
4 O70174 (/ISO) O70174 (/ISO) Q2MKA5 (/ISO) Q8R4G9 (/ISO)
Channel activity GO:0015267
Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
3 Q05901 (/TAS) Q05901 (/TAS) Q05901 (/TAS)
Ligand-gated ion channel activity GO:0015276
Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
3 P30532 (/TAS) P32297 (/TAS) P43681 (/TAS)
Acetylcholine-gated cation-selective channel activity GO:0022848
Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
3 O70174 (/IGI) O70174 (/IGI) P04757 (/IGI)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
3 P04757 (/IDA) P09483 (/IDA) P20420 (/IDA)
Ion channel activity GO:0005216
Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
2 O70174 (/IDA) O70174 (/IDA)
Acetylcholine receptor activity GO:0015464
Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2 Q15825 (/TAS) Q15825 (/TAS)
Acetylcholine-gated cation-selective channel activity GO:0022848
Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
2 P09483 (/IC) P12391 (/IC)
Acetylcholine binding GO:0042166
Interacting selectively and non-covalently with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.
2 P32297 (/IC) P43681 (/IC)
Transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:1904315
Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.
2 P09483 (/IDA) Q8R4G9 (/IDA)
Transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:1904315
Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.
2 O70174 (/ISO) O70174 (/ISO)
Acetylcholine-gated cation-selective channel activity GO:0022848
Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
1 P30532 (/NAS)
Transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:1904315
Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.
1 P09483 (/EXP)
Transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential GO:1904315
Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.
1 Q8R4G9 (/IMP)

There are 97 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Behavioral response to nicotine GO:0035095
Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.
9 B3DGY1 (/IMP) O70174 (/IMP) O70174 (/IMP) P30532 (/IMP) P32297 (/IMP) P43681 (/IMP) Q1RLX8 (/IMP) Q7ZZP7 (/IMP) Q8R4G9 (/IMP)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
7 P18845 (/ISS) Q07263 (/ISS) Q19AE6 (/ISS) Q5IS76 (/ISS) Q5IS76 (/ISS) Q5IS77 (/ISS) Q5IS77 (/ISS)
Behavioral response to nicotine GO:0035095
Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.
7 P18845 (/ISS) Q07263 (/ISS) Q19AE6 (/ISS) Q5IS76 (/ISS) Q5IS76 (/ISS) Q5IS77 (/ISS) Q5IS77 (/ISS)
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
6 B3DGY1 (/IMP) O70174 (/IMP) O70174 (/IMP) Q1RLX8 (/IMP) Q2MKA5 (/IMP) Q7ZZP7 (/IMP)
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
6 O70174 (/ISO) O70174 (/ISO) Q8BMN3 (/ISO) Q8R4G9 (/ISO) Q91X60 (/ISO) Q9R0W9 (/ISO)
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
6 O70174 (/IDA) O70174 (/IDA) P04757 (/IDA) Q2MKA5 (/IDA) Q8BMN3 (/IDA) Q9R0W9 (/IDA)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
5 Q05901 (/TAS) Q05901 (/TAS) Q05901 (/TAS) Q15825 (/TAS) Q15825 (/TAS)
Protein heterooligomerization GO:0051291
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
5 P04757 (/IDA) P09483 (/IDA) P12389 (/IDA) P12391 (/IDA) P43143 (/IDA)
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
5 O70174 (/IMP) O70174 (/IMP) Q2MKA5 (/IMP) Q8BMN3 (/IMP) Q9R0W9 (/IMP)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
4 O70174 (/ISO) O70174 (/ISO) Q8R4G9 (/ISO) Q91X60 (/ISO)
Synaptic transmission, cholinergic GO:0007271
The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
4 O70174 (/IMP) O70174 (/IMP) P09483 (/IMP) Q8R4G9 (/IMP)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
4 P18845 (/ISS) Q07263 (/ISS) Q5IS76 (/ISS) Q5IS76 (/ISS)
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
4 O70174 (/IDA) O70174 (/IDA) P43681 (/IDA) Q0PJT8 (/IDA)
Behavioral response to nicotine GO:0035095
Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.
4 O70174 (/ISO) O70174 (/ISO) Q2MKA5 (/ISO) Q8R4G9 (/ISO)
Synaptic transmission involved in micturition GO:0060084
The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body.
4 P18845 (/ISS) Q07263 (/ISS) Q5IS76 (/ISS) Q5IS76 (/ISS)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
3 Q19AE6 (/ISS) Q5IS77 (/ISS) Q5IS77 (/ISS)
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
3 Q19AE6 (/ISS) Q5IS77 (/ISS) Q5IS77 (/ISS)
Ion transport GO:0006811
The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 P32297 (/NAS) P43681 (/NAS) Q15822 (/NAS)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
3 Q19AE6 (/ISS) Q5IS77 (/ISS) Q5IS77 (/ISS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
3 P32297 (/IDA) P43681 (/IDA) Q15822 (/IDA)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
3 P30532 (/TAS) Q15825 (/TAS) Q15825 (/TAS)
Synaptic transmission, cholinergic GO:0007271
The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
3 Q05901 (/TAS) Q05901 (/TAS) Q05901 (/TAS)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
3 O70174 (/IMP) O70174 (/IMP) Q8R4G9 (/IMP)
Regulation of dopamine secretion GO:0014059
Any process that modulates the frequency, rate or extent of the regulated release of dopamine.
3 O70174 (/IMP) O70174 (/IMP) Q9R0W9 (/IMP)
Positive regulation of dopamine secretion GO:0033603
Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.
3 O70174 (/ISO) O70174 (/ISO) Q9R0W9 (/ISO)
Nervous system process GO:0050877
A organ system process carried out by any of the organs or tissues of neurological system.
3 O70174 (/IMP) O70174 (/IMP) P43681 (/IMP)
Nervous system process GO:0050877
A organ system process carried out by any of the organs or tissues of neurological system.
3 Q19AE6 (/ISS) Q5IS77 (/ISS) Q5IS77 (/ISS)
Cognition GO:0050890
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
3 Q19AE6 (/ISS) Q5IS77 (/ISS) Q5IS77 (/ISS)
Membrane depolarization GO:0051899
The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.
3 O70174 (/IMP) O70174 (/IMP) Q9R0W9 (/IMP)
Action potential GO:0001508
A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.
2 O70174 (/IMP) O70174 (/IMP)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
2 O70174 (/ISO) O70174 (/ISO)
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
2 O70174 (/ISO) O70174 (/ISO)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2 O70174 (/IGI) O70174 (/IGI)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 O70174 (/ISO) O70174 (/ISO)
Synaptic transmission, cholinergic GO:0007271
The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
2 O70174 (/IDA) O70174 (/IDA)
Synaptic transmission, cholinergic GO:0007271
The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
2 O70174 (/ISO) O70174 (/ISO)
Synaptic transmission, cholinergic GO:0007271
The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
2 P32297 (/ISS) P43681 (/ISS)
Respiratory gaseous exchange by respiratory system GO:0007585
The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms.
2 O70174 (/IMP) O70174 (/IMP)
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
2 O70174 (/IMP) O70174 (/IMP)
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
2 O70174 (/TAS) O70174 (/TAS)
Positive regulation of dopamine secretion GO:0033603
Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.
2 P09483 (/IDA) P43143 (/IDA)
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
2 O70174 (/IGI) O70174 (/IGI)
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
2 O70174 (/ISO) O70174 (/ISO)
Exploration behavior GO:0035640
The specific behavior of an organism in response to a novel environment or stimulus.
2 O70174 (/IMP) O70174 (/IMP)
B cell activation GO:0042113
The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
2 O70174 (/IMP) O70174 (/IMP)
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
2 O70174 (/IGI) O70174 (/IGI)
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
2 P32297 (/ISS) P43681 (/ISS)
Nervous system process GO:0050877
A organ system process carried out by any of the organs or tissues of neurological system.
2 O70174 (/ISO) O70174 (/ISO)
Cognition GO:0050890
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
2 O70174 (/ISO) O70174 (/ISO)
Membrane depolarization GO:0051899
The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.
2 O70174 (/IGI) O70174 (/IGI)
Inhibitory postsynaptic potential GO:0060080
A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
2 O70174 (/IMP) O70174 (/IMP)
Synaptic transmission involved in micturition GO:0060084
The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body.
2 P32297 (/IMP) Q8R4G9 (/IMP)
Acetylcholine receptor signaling pathway GO:0095500
The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.
2 O70174 (/IDA) O70174 (/IDA)
Regulation of acetylcholine-gated cation channel activity GO:1903048
Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity.
2 O70174 (/ISO) O70174 (/ISO)
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
2 P04757 (/EXP) Q8BMN3 (/EXP)
Action potential GO:0001508
A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.
1 P43681 (/ISS)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 P43681 (/IDA)
DNA repair GO:0006281
The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
1 P43681 (/IMP)
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P43681 (/ISS)
Regulation of muscle contraction GO:0006937
Any process that modulates the frequency, rate or extent of muscle contraction.
1 Q8R4G9 (/IMP)
Regulation of smooth muscle contraction GO:0006940
Any process that modulates the frequency, rate or extent of smooth muscle contraction.
1 Q8R4G9 (/IMP)
Regulation of smooth muscle contraction GO:0006940
Any process that modulates the frequency, rate or extent of smooth muscle contraction.
1 P32297 (/ISS)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 P43681 (/IMP)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 P30532 (/NAS)
Activation of transmembrane receptor protein tyrosine kinase activity GO:0007171
Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity.
1 Q8R4G9 (/IMP)
Activation of transmembrane receptor protein tyrosine kinase activity GO:0007171
Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity.
1 P32297 (/ISS)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
1 P43681 (/NAS)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
1 P32297 (/IMP)
Nervous system development GO:0007399
The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
1 Q8R4G9 (/ISO)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
1 P04757 (/IEP)
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
1 P32297 (/ISS)
Response to inorganic substance GO:0010035
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
1 P04757 (/IEP)
Regulation of acetylcholine secretion, neurotransmission GO:0014056
Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.
1 Q8R4G9 (/IMP)
Regulation of acetylcholine secretion, neurotransmission GO:0014056
Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.
1 P32297 (/ISS)
Regulation of dopamine secretion GO:0014059
Any process that modulates the frequency, rate or extent of the regulated release of dopamine.
1 P43681 (/ISS)
Sensory perception of pain GO:0019233
The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
1 P43681 (/ISS)
Response to nicotine GO:0035094
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
1 P04757 (/IEP)
B cell activation GO:0042113
The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
1 P43681 (/ISS)
Regulation of membrane potential GO:0042391
Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
1 Q8R4G9 (/IMP)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 P04757 (/IDA)
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q8R4G9 (/ISO)
Regulation of dendrite morphogenesis GO:0048814
Any process that modulates the frequency, rate or extent of dendrite morphogenesis.
1 Q8R4G9 (/IMP)
Regulation of dendrite morphogenesis GO:0048814
Any process that modulates the frequency, rate or extent of dendrite morphogenesis.
1 P32297 (/ISS)
Cognition GO:0050890
The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
1 P43681 (/IMP)
Membrane depolarization GO:0051899
The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.
1 P43681 (/ISS)
Excitatory postsynaptic potential GO:0060079
A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
1 Q8R4G9 (/IMP)
Excitatory postsynaptic potential GO:0060079
A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
1 P32297 (/ISS)
Inhibitory postsynaptic potential GO:0060080
A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
1 P43681 (/ISS)
Synaptic transmission involved in micturition GO:0060084
The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body.
1 Q8R4G9 (/ISO)
Acetylcholine receptor signaling pathway GO:0095500
The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.
1 P04757 (/IGI)
Acetylcholine receptor signaling pathway GO:0095500
The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.
1 Q8R4G9 (/ISO)
Acetylcholine receptor signaling pathway GO:0095500
The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.
1 P32297 (/ISS)
Regulation of acetylcholine-gated cation channel activity GO:1903048
Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity.
1 P09483 (/IMP)
Response to acetylcholine GO:1905144
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.
1 P04757 (/IGI)
Response to acetylcholine GO:1905144
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.
1 Q8R4G9 (/ISO)
Response to acetylcholine GO:1905144
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.
1 P32297 (/ISS)
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
1 Q8R4G9 (/ISO)

There are 48 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Acetylcholine-gated channel complex GO:0005892
A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
16 B3DGY1 (/IDA) O70174 (/IDA) O70174 (/IDA) P04757 (/IDA) P09483 (/IDA) P12389 (/IDA) P12391 (/IDA) P20420 (/IDA) P32297 (/IDA) P43143 (/IDA)
(6 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 P30532 (/TAS) P32297 (/TAS) P43681 (/TAS) Q05901 (/TAS) Q05901 (/TAS) Q05901 (/TAS) Q15822 (/TAS) Q15825 (/TAS) Q15825 (/TAS)
Acetylcholine-gated channel complex GO:0005892
A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
8 P04757 (/TAS) P09483 (/TAS) P12391 (/TAS) Q05901 (/TAS) Q05901 (/TAS) Q05901 (/TAS) Q15825 (/TAS) Q15825 (/TAS)
Acetylcholine-gated channel complex GO:0005892
A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
7 O70174 (/ISO) O70174 (/ISO) Q2MKA5 (/ISO) Q8BMN3 (/ISO) Q8R4G9 (/ISO) Q91X60 (/ISO) Q9R0W9 (/ISO)
Acetylcholine-gated channel complex GO:0005892
A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
7 P18845 (/ISS) Q07263 (/ISS) Q19AE6 (/ISS) Q5IS76 (/ISS) Q5IS76 (/ISS) Q5IS77 (/ISS) Q5IS77 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
7 O70174 (/IDA) O70174 (/IDA) P04757 (/IDA) P09483 (/IDA) P12389 (/IDA) P12391 (/IDA) P43143 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
6 O70174 (/ISO) O70174 (/ISO) Q8BMN3 (/ISO) Q8R4G9 (/ISO) Q91X60 (/ISO) Q9R0W9 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
6 P32297 (/NAS) P43681 (/NAS) Q05901 (/NAS) Q05901 (/NAS) Q05901 (/NAS) Q15822 (/NAS)
Dopaminergic synapse GO:0098691
A synapse that uses dopamine as a neurotransmitter.
6 O70174 (/IDA) O70174 (/IDA) P04757 (/IDA) Q2MKA5 (/IDA) Q8BMN3 (/IDA) Q9R0W9 (/IDA)
Dopaminergic synapse GO:0098691
A synapse that uses dopamine as a neurotransmitter.
5 O70174 (/IMP) O70174 (/IMP) Q2MKA5 (/IMP) Q8BMN3 (/IMP) Q9R0W9 (/IMP)
Integral component of presynaptic membrane GO:0099056
The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5 O70174 (/IDA) O70174 (/IDA) P09483 (/IDA) P43143 (/IDA) Q9R0W9 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 B8ZZD3 (/IDA) O70174 (/IDA) O70174 (/IDA) P20420 (/IDA)
Acetylcholine-gated channel complex GO:0005892
A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
4 O70174 (/IPI) O70174 (/IPI) Q2MKA5 (/IPI) Q8R4G9 (/IPI)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
4 O70174 (/ISO) O70174 (/ISO) Q2MKA5 (/ISO) Q8R4G9 (/ISO)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
4 O70174 (/ISO) O70174 (/ISO) Q2MKA5 (/ISO) Q8R4G9 (/ISO)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
3 P04757 (/IDA) P09483 (/IDA) P20420 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
3 P04757 (/IDA) P09483 (/IDA) P20420 (/IDA)
Cholinergic synapse GO:0098981
A synapse that uses acetylcholine as a neurotransmitter.
3 P04757 (/IDA) P09483 (/IDA) Q8R4G9 (/IDA)
Cholinergic synapse GO:0098981
A synapse that uses acetylcholine as a neurotransmitter.
3 O70174 (/ISO) O70174 (/ISO) Q8R4G9 (/ISO)
Integral component of presynaptic membrane GO:0099056
The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 O70174 (/ISO) O70174 (/ISO) Q9R0W9 (/ISO)
Integral component of postsynaptic specialization membrane GO:0099060
The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 P04757 (/IDA) P09483 (/IDA) Q8R4G9 (/IDA)
Integral component of postsynaptic specialization membrane GO:0099060
The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
3 O70174 (/ISO) O70174 (/ISO) Q8R4G9 (/ISO)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
2 O70174 (/IDA) O70174 (/IDA)
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
2 P32297 (/ISS) P43681 (/ISS)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
2 P32297 (/ISS) P43681 (/ISS)
Dopaminergic synapse GO:0098691
A synapse that uses dopamine as a neurotransmitter.
2 P04757 (/EXP) Q8BMN3 (/EXP)
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 P43143 (/IDA) Q9R0W9 (/IDA)
Integral component of presynaptic membrane GO:0099056
The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
2 O70174 (/IMP) O70174 (/IMP)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q2MKA5 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 P43681 (/ISS)
Acetylcholine-gated channel complex GO:0005892
A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
1 P30532 (/IC)
Acetylcholine-gated channel complex GO:0005892
A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
1 P04757 (/IGI)
External side of plasma membrane GO:0009897
The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
1 P43681 (/ISS)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
1 P04757 (/IDA)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
1 Q8R4G9 (/ISO)
Postsynaptic density GO:0014069
An electron dense network of proteins within and adjacent to the postsynaptic membrane of an asymmetric, neuron-neuron synapse. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
1 P32297 (/ISS)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 P43681 (/ISS)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 P12391 (/IDA)
Neuron projection GO:0043005
A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1 Q8BMN3 (/ISO)
Plasma membrane raft GO:0044853
A membrane raft that is part of the plasma membrane.
1 P04757 (/IGI)
Plasma membrane raft GO:0044853
A membrane raft that is part of the plasma membrane.
1 Q8R4G9 (/ISO)
Plasma membrane raft GO:0044853
A membrane raft that is part of the plasma membrane.
1 P32297 (/ISS)
Postsynaptic membrane GO:0045211
A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
1 Q8R4G9 (/IC)
Cell periphery GO:0071944
The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
1 Q91X60 (/IDA)
Dopaminergic synapse GO:0098691
A synapse that uses dopamine as a neurotransmitter.
1 Q8R4G9 (/ISO)
Cholinergic synapse GO:0098981
A synapse that uses acetylcholine as a neurotransmitter.
1 P09483 (/EXP)
Cholinergic synapse GO:0098981
A synapse that uses acetylcholine as a neurotransmitter.
1 Q8R4G9 (/IMP)
Integral component of postsynaptic membrane GO:0099055
The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q9R0W9 (/ISO)