The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Formin, FH2 domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 9: Disheveled-associated activator of morphogenesis

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 14 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Axon guidance GO:0007411
The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
6 M9MSM5 (/IMP) Q5BII2 (/IMP) Q7YZA4 (/IMP) Q8IRY0 (/IMP) Q8MT16 (/IMP) Q9W5A4 (/IMP)
Open tracheal system development GO:0007424
The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
6 M9MSM5 (/IMP) Q5BII2 (/IMP) Q7YZA4 (/IMP) Q8IRY0 (/IMP) Q8MT16 (/IMP) Q9W5A4 (/IMP)
Mushroom body development GO:0016319
The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
6 M9MSM5 (/IMP) Q5BII2 (/IMP) Q7YZA4 (/IMP) Q8IRY0 (/IMP) Q8MT16 (/IMP) Q9W5A4 (/IMP)
Positive regulation of actin filament polymerization GO:0030838
Any process that activates or increases the frequency, rate or extent of actin polymerization.
6 M9MSM5 (/IGI) Q5BII2 (/IGI) Q7YZA4 (/IGI) Q8IRY0 (/IGI) Q8MT16 (/IGI) Q9W5A4 (/IGI)
Positive regulation of actin filament polymerization GO:0030838
Any process that activates or increases the frequency, rate or extent of actin polymerization.
6 M9MSM5 (/IMP) Q5BII2 (/IMP) Q7YZA4 (/IMP) Q8IRY0 (/IMP) Q8MT16 (/IMP) Q9W5A4 (/IMP)
Regulation of tube architecture, open tracheal system GO:0035152
Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network.
6 M9MSM5 (/IMP) Q5BII2 (/IMP) Q7YZA4 (/IMP) Q8IRY0 (/IMP) Q8MT16 (/IMP) Q9W5A4 (/IMP)
Axon extension GO:0048675
Long distance growth of a single axon process involved in cellular development.
6 M9MSM5 (/IGI) Q5BII2 (/IGI) Q7YZA4 (/IGI) Q8IRY0 (/IGI) Q8MT16 (/IGI) Q9W5A4 (/IGI)
Axon extension GO:0048675
Long distance growth of a single axon process involved in cellular development.
6 M9MSM5 (/IMP) Q5BII2 (/IMP) Q7YZA4 (/IMP) Q8IRY0 (/IMP) Q8MT16 (/IMP) Q9W5A4 (/IMP)
Regulation of axonogenesis GO:0050770
Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
6 M9MSM5 (/IDA) Q5BII2 (/IDA) Q7YZA4 (/IDA) Q8IRY0 (/IDA) Q8MT16 (/IDA) Q9W5A4 (/IDA)
Actin filament bundle assembly GO:0051017
The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
6 M9MSM5 (/IMP) Q5BII2 (/IMP) Q7YZA4 (/IMP) Q8IRY0 (/IMP) Q8MT16 (/IMP) Q9W5A4 (/IMP)
Regulation of filopodium assembly GO:0051489
Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
6 M9MSM5 (/IDA) Q5BII2 (/IDA) Q7YZA4 (/IDA) Q8IRY0 (/IDA) Q8MT16 (/IDA) Q9W5A4 (/IDA)
Positive regulation of filopodium assembly GO:0051491
Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
6 M9MSM5 (/IMP) Q5BII2 (/IMP) Q7YZA4 (/IMP) Q8IRY0 (/IMP) Q8MT16 (/IMP) Q9W5A4 (/IMP)
Positive regulation of sarcomere organization GO:0060298
Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
6 M9MSM5 (/IGI) Q5BII2 (/IGI) Q7YZA4 (/IGI) Q8IRY0 (/IGI) Q8MT16 (/IGI) Q9W5A4 (/IGI)
Muscle thin filament assembly GO:0071689
The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.
6 M9MSM5 (/IGI) Q5BII2 (/IGI) Q7YZA4 (/IGI) Q8IRY0 (/IGI) Q8MT16 (/IGI) Q9W5A4 (/IGI)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Striated muscle thin filament GO:0005865
Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.
6 M9MSM5 (/IDA) Q5BII2 (/IDA) Q7YZA4 (/IDA) Q8IRY0 (/IDA) Q8MT16 (/IDA) Q9W5A4 (/IDA)
Sarcoplasm GO:0016528
The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum.
6 M9MSM5 (/IDA) Q5BII2 (/IDA) Q7YZA4 (/IDA) Q8IRY0 (/IDA) Q8MT16 (/IDA) Q9W5A4 (/IDA)
Z disc GO:0030018
Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
6 M9MSM5 (/IDA) Q5BII2 (/IDA) Q7YZA4 (/IDA) Q8IRY0 (/IDA) Q8MT16 (/IDA) Q9W5A4 (/IDA)
Axonal growth cone GO:0044295
The migrating motile tip of a growing nerve cell axon.
6 M9MSM5 (/IDA) Q5BII2 (/IDA) Q7YZA4 (/IDA) Q8IRY0 (/IDA) Q8MT16 (/IDA) Q9W5A4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q8IRY0 (/TAS)
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