The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Formin, FH2 domain
".
FunFam 4: Formin homology 2 domain-containing 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q2V2M9 (/IPI) Q9Y613 (/IPI) |
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | Q9Y613 (/IPI) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q9Y613 (/IPI) |
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
1 | Q9Y613 (/IMP) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Muscle system process GO:0003012
A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.
|
10 | E1JI78 (/IEP) M9MRS9 (/IEP) M9MSK7 (/IEP) M9ND66 (/IEP) M9NE63 (/IEP) M9NFP9 (/IEP) Q8SY43 (/IEP) Q8T4F5 (/IEP) Q9VSQ0 (/IEP) Q9VSQ1 (/IEP) |
Muscle system process GO:0003012
A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.
|
10 | E1JI78 (/IGI) M9MRS9 (/IGI) M9MSK7 (/IGI) M9ND66 (/IGI) M9NE63 (/IGI) M9NFP9 (/IGI) Q8SY43 (/IGI) Q8T4F5 (/IGI) Q9VSQ0 (/IGI) Q9VSQ1 (/IGI) |
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
|
10 | E1JI78 (/IMP) M9MRS9 (/IMP) M9MSK7 (/IMP) M9ND66 (/IMP) M9NE63 (/IMP) M9NFP9 (/IMP) Q8SY43 (/IMP) Q8T4F5 (/IMP) Q9VSQ0 (/IMP) Q9VSQ1 (/IMP) |
Programmed cell death involved in cell development GO:0010623
The activation of endogenous cellular processes that result in the death of a cell as part of its development.
|
10 | E1JI78 (/IMP) M9MRS9 (/IMP) M9MSK7 (/IMP) M9ND66 (/IMP) M9NE63 (/IMP) M9NFP9 (/IMP) Q8SY43 (/IMP) Q8T4F5 (/IMP) Q9VSQ0 (/IMP) Q9VSQ1 (/IMP) |
Positive regulation of cell migration GO:0030335
Any process that activates or increases the frequency, rate or extent of cell migration.
|
10 | E1JI78 (/IMP) M9MRS9 (/IMP) M9MSK7 (/IMP) M9ND66 (/IMP) M9NE63 (/IMP) M9NFP9 (/IMP) Q8SY43 (/IMP) Q8T4F5 (/IMP) Q9VSQ0 (/IMP) Q9VSQ1 (/IMP) |
Salivary gland histolysis GO:0035070
The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.
|
10 | E1JI78 (/IMP) M9MRS9 (/IMP) M9MSK7 (/IMP) M9ND66 (/IMP) M9NE63 (/IMP) M9NFP9 (/IMP) Q8SY43 (/IMP) Q8T4F5 (/IMP) Q9VSQ0 (/IMP) Q9VSQ1 (/IMP) |
Wound healing, spreading of cells GO:0044319
The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface.
|
10 | E1JI78 (/IMP) M9MRS9 (/IMP) M9MSK7 (/IMP) M9ND66 (/IMP) M9NE63 (/IMP) M9NFP9 (/IMP) Q8SY43 (/IMP) Q8T4F5 (/IMP) Q9VSQ0 (/IMP) Q9VSQ1 (/IMP) |
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
|
10 | E1JI78 (/IGI) M9MRS9 (/IGI) M9MSK7 (/IGI) M9ND66 (/IGI) M9NE63 (/IGI) M9NFP9 (/IGI) Q8SY43 (/IGI) Q8T4F5 (/IGI) Q9VSQ0 (/IGI) Q9VSQ1 (/IGI) |
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
|
10 | E1JI78 (/IMP) M9MRS9 (/IMP) M9MSK7 (/IMP) M9ND66 (/IMP) M9NE63 (/IMP) M9NFP9 (/IMP) Q8SY43 (/IMP) Q8T4F5 (/IMP) Q9VSQ0 (/IMP) Q9VSQ1 (/IMP) |
Positive regulation of stress fiber assembly GO:0051496
Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
|
10 | E1JI78 (/IGI) M9MRS9 (/IGI) M9MSK7 (/IGI) M9ND66 (/IGI) M9NE63 (/IGI) M9NFP9 (/IGI) Q8SY43 (/IGI) Q8T4F5 (/IGI) Q9VSQ0 (/IGI) Q9VSQ1 (/IGI) |
Positive regulation of stress fiber assembly GO:0051496
Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
|
10 | E1JI78 (/IMP) M9MRS9 (/IMP) M9MSK7 (/IMP) M9ND66 (/IMP) M9NE63 (/IMP) M9NFP9 (/IMP) Q8SY43 (/IMP) Q8T4F5 (/IMP) Q9VSQ0 (/IMP) Q9VSQ1 (/IMP) |
Trachea morphogenesis GO:0060439
The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.
|
10 | E1JI78 (/IMP) M9MRS9 (/IMP) M9MSK7 (/IMP) M9ND66 (/IMP) M9NE63 (/IMP) M9NFP9 (/IMP) Q8SY43 (/IMP) Q8T4F5 (/IMP) Q9VSQ0 (/IMP) Q9VSQ1 (/IMP) |
Positive regulation of substrate adhesion-dependent cell spreading GO:1900026
Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
|
10 | E1JI78 (/IMP) M9MRS9 (/IMP) M9MSK7 (/IMP) M9ND66 (/IMP) M9NE63 (/IMP) M9NFP9 (/IMP) Q8SY43 (/IMP) Q8T4F5 (/IMP) Q9VSQ0 (/IMP) Q9VSQ1 (/IMP) |
Nuclear migration GO:0007097
The directed movement of the nucleus to a specific location within a cell.
|
1 | Q6P9Q4 (/IMP) |
Negative regulation of actin filament polymerization GO:0030837
Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.
|
1 | Q76LL6 (/IDA) |
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
1 | Q76LL6 (/IGI) |
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
1 | F1LQJ2 (/IMP) |
Sarcomere organization GO:0045214
The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
1 | Q76LL6 (/ISO) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q9Y613 (/IDA) |
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q9Y613 (/IMP) |
Regulation of stress fiber assembly GO:0051492
Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
|
1 | Q9Y613 (/IMP) |
Positive regulation of stress fiber assembly GO:0051496
Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
|
1 | Q9Y613 (/IDA) |
Establishment of centrosome localization GO:0051660
The directed movement of the centrosome to a specific location.
|
1 | Q6P9Q4 (/IMP) |
Cardiac myofibril assembly GO:0055003
The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
|
1 | Q76LL6 (/IMP) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
11 |
E1JI78 (/IDA)
M9MRS9 (/IDA)
M9MSK7 (/IDA)
M9ND66 (/IDA)
M9NE63 (/IDA)
M9NFP9 (/IDA)
Q8SY43 (/IDA)
Q8T4F5 (/IDA)
Q9VSQ0 (/IDA)
Q9VSQ1 (/IDA)
(1 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
10 | E1JI78 (/IDA) M9MRS9 (/IDA) M9MSK7 (/IDA) M9ND66 (/IDA) M9NE63 (/IDA) M9NFP9 (/IDA) Q8SY43 (/IDA) Q8T4F5 (/IDA) Q9VSQ0 (/IDA) Q9VSQ1 (/IDA) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
10 | E1JI78 (/IDA) M9MRS9 (/IDA) M9MSK7 (/IDA) M9ND66 (/IDA) M9NE63 (/IDA) M9NFP9 (/IDA) Q8SY43 (/IDA) Q8T4F5 (/IDA) Q9VSQ0 (/IDA) Q9VSQ1 (/IDA) |
Intercalated disc GO:0014704
A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.
|
2 | I3LJ91 (/IDA) Q6P9Q4 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9Y613 (/TAS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9Y613 (/IDA) |
Striated muscle thin filament GO:0005865
Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.
|
1 | F1LQJ2 (/IDA) |
Striated muscle thin filament GO:0005865
Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.
|
1 | Q76LL6 (/ISO) |
Adherens junction GO:0005912
A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
|
1 | I3LJ91 (/IDA) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9Y613 (/HDA) |