The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Phosphate transport system protein phou homolog 2; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Phosphate-specific transport system accessory prot...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
237 B6ZCF1 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS)
(227 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
96 P0A9K7 (/IPI) P0A9K7 (/IPI) P0A9K7 (/IPI) P0A9K7 (/IPI) P0A9K7 (/IPI) P0A9K7 (/IPI) P0A9K7 (/IPI) P0A9K7 (/IPI) P0A9K7 (/IPI) P0A9K7 (/IPI)
(86 more)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
92 P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA)
(82 more)
Manganese ion binding GO:0030145
Interacting selectively and non-covalently with manganese (Mn) ions.
92 P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA)
(82 more)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 O67053 (/IDA)

There are 25 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of phosphate transmembrane transport GO:2000186
Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport.
145 B6ZCF1 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS)
(135 more)
Negative regulation of phosphate metabolic process GO:0045936
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
142 B6ZCF1 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS)
(132 more)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
128 B6ZCF1 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS)
(118 more)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
100 P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP)
(90 more)
Negative regulation of phosphate metabolic process GO:0045936
Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
96 P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP)
(86 more)
Regulation of cell growth GO:0001558
Any process that modulates the frequency, rate, extent or direction of cell growth.
92 P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP)
(82 more)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
92 P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP)
(82 more)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
92 P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP)
(82 more)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
92 P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS)
(82 more)
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
92 P0A9K7 (/IEP) P0A9K7 (/IEP) P0A9K7 (/IEP) P0A9K7 (/IEP) P0A9K7 (/IEP) P0A9K7 (/IEP) P0A9K7 (/IEP) P0A9K7 (/IEP) P0A9K7 (/IEP) P0A9K7 (/IEP)
(82 more)
Cellular phosphate ion homeostasis GO:0030643
Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell.
92 P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS) P0A9K7 (/TAS)
(82 more)
Negative regulation of ion transmembrane transporter activity GO:0032413
Any process that stops or reduces the activity of an ion transporter.
92 P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP)
(82 more)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
92 P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP)
(82 more)
Cellular response to antibiotic GO:0071236
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
92 P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP)
(82 more)
Cellular response to pH GO:0071467
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
92 P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP)
(82 more)
Negative regulation of phosphate transmembrane transport GO:2000186
Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport.
92 P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP) P0A9K7 (/IMP)
(82 more)
Negative regulation of chemotaxis GO:0050922
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
9 Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP)
Negative regulation of positive chemotaxis GO:0050928
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
9 Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP)
Cell chemotaxis GO:0060326
The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
9 Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP) Q51547 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
4 Q83WB2 (/IMP) Q83WB2 (/IMP) Q83WB2 (/IMP) Q83WB2 (/IMP)
Regulation of phosphate metabolic process GO:0019220
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
4 Q83WB2 (/IEP) Q83WB2 (/IEP) Q83WB2 (/IEP) Q83WB2 (/IEP)
Phosphate-containing compound metabolic process GO:0006796
The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
1 Q8EG81 (/ISS)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 O67053 (/NAS)
Regulation of phosphate metabolic process GO:0019220
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
1 B6ZCF1 (/IGC)
Negative regulation of phosphate transmembrane transport GO:2000186
Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport.
1 O67053 (/NAS)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
145 B6ZCF1 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS) O32488 (/ISS)
(135 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
93 O67053 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA)
(83 more)
Extrinsic component of plasma membrane GO:0019897
The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
92 P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA) P0A9K7 (/IDA)
(82 more)
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