CATH Superfamily 1.20.58.2170

FunFam 1: Death domain-associated protein 6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 39 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Transcription corepressor activity GO:0003714 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.	10	A3KNT2 (/IDA) A7E2H6 (/IDA) F1QQQ8 (/IDA) Q1LUU4 (/IDA) Q567Z8 (/IDA) Q6DEL6 (/IDA) Q7ZZ71 (/IDA) Q9UER7 (/IDA) Q9UER7 (/IDA) Q9W7B2 (/IDA)
Protein binding GO:0005515 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	8	O35613 (/IPI) Q5UDQ8 (/IPI) Q8VIB2 (/IPI) Q8WSS9 (/IPI) Q95TR4 (/IPI) Q9UER7 (/IPI) Q9UER7 (/IPI) Q9VMD0 (/IPI)
Transcription factor binding GO:0008134 Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.	5	O18805 (/ISS) O35613 (/ISS) Q5RAL6 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Protein homodimerization activity GO:0042803 Interacting selectively and non-covalently with an identical protein to form a homodimer.	5	O18805 (/ISS) O35613 (/ISS) Q5RAL6 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	3	O35613 (/IDA) Q9UER7 (/IDA) Q9UER7 (/IDA)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	3	O18805 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Transcription corepressor activity GO:0003714 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.	3	O18805 (/IMP) Q9UER7 (/IMP) Q9UER7 (/IMP)
Protein kinase binding GO:0019901 Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.	3	Q8VIB2 (/IPI) Q9UER7 (/IPI) Q9UER7 (/IPI)
Histone binding GO:0042393 Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.	3	O35613 (/IDA) Q9UER7 (/IDA) Q9UER7 (/IDA)
Androgen receptor binding GO:0050681 Interacting selectively and non-covalently with an androgen receptor.	3	Q8VIB2 (/IPI) Q9UER7 (/IPI) Q9UER7 (/IPI)
P53 binding GO:0002039 Interacting selectively and non-covalently with one of the p53 family of proteins.	2	Q9UER7 (/IPI) Q9UER7 (/IPI)
Enzyme binding GO:0019899 Interacting selectively and non-covalently with any enzyme.	2	Q9UER7 (/IPI) Q9UER7 (/IPI)
Protein kinase activator activity GO:0030295 Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.	2	Q9UER7 (/IGI) Q9UER7 (/IGI)
Heat shock protein binding GO:0031072 Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.	2	Q9UER7 (/TAS) Q9UER7 (/TAS)
Ubiquitin protein ligase binding GO:0031625 Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.	2	Q9UER7 (/IPI) Q9UER7 (/IPI)
SUMO binding GO:0032183 Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO.	2	Q9UER7 (/IPI) Q9UER7 (/IPI)
Protein heterodimerization activity GO:0046982 Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Protein N-terminus binding GO:0047485 Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.	2	Q9UER7 (/IPI) Q9UER7 (/IPI)
P53 binding GO:0002039 Interacting selectively and non-covalently with one of the p53 family of proteins.	1	O35613 (/ISO)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	1	O35613 (/ISO)
Transcription corepressor activity GO:0003714 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.	1	O35613 (/ISO)
Transcription corepressor activity GO:0003714 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.	1	O35613 (/TAS)
Transcription factor binding GO:0008134 Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.	1	Q8VIB2 (/IPI)
Transcription factor binding GO:0008134 Interacting selectively and non-covalently with a transcription factor, a protein required to initiate or regulate transcription.	1	O35613 (/ISO)
JUN kinase binding GO:0008432 Interacting selectively and non-covalently with JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family.	1	Q8VIB2 (/IPI)
JUN kinase binding GO:0008432 Interacting selectively and non-covalently with JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family.	1	O35613 (/ISO)
Kinesin binding GO:0019894 Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.	1	Q8VIB2 (/IPI)
Kinesin binding GO:0019894 Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.	1	O35613 (/ISO)
Enzyme binding GO:0019899 Interacting selectively and non-covalently with any enzyme.	1	O35613 (/ISO)
Protein kinase binding GO:0019901 Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.	1	O35613 (/ISO)
Protein kinase activator activity GO:0030295 Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.	1	O35613 (/ISO)
Ubiquitin protein ligase binding GO:0031625 Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.	1	O35613 (/ISO)
SUMO binding GO:0032183 Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO.	1	O35613 (/ISO)
Histone binding GO:0042393 Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.	1	O35613 (/ISO)
Protein homodimerization activity GO:0042803 Interacting selectively and non-covalently with an identical protein to form a homodimer.	1	O35613 (/ISO)
Protein heterodimerization activity GO:0046982 Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.	1	O35613 (/ISO)
Protein N-terminus binding GO:0047485 Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.	1	O35613 (/ISO)
Androgen receptor binding GO:0050681 Interacting selectively and non-covalently with an androgen receptor.	1	O35613 (/ISO)
Androgen receptor binding GO:0050681 Interacting selectively and non-covalently with an androgen receptor.	1	O35613 (/ISS)

There are 69 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	5	O18805 (/ISS) O35613 (/ISS) Q5RAL6 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Response to oxidative stress GO:0006979 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	4	Q5UDQ8 (/IMP) Q8WSS9 (/IMP) Q95TR4 (/IMP) Q9VMD0 (/IMP)
Determination of adult lifespan GO:0008340 The control of viability and duration in the adult phase of the life-cycle.	4	Q5UDQ8 (/IMP) Q8WSS9 (/IMP) Q95TR4 (/IMP) Q9VMD0 (/IMP)
Regulation of protein ubiquitination GO:0031396 Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.	4	O18805 (/ISS) O35613 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Cellular response to heat GO:0034605 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	4	O18805 (/ISS) O35613 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Cellular response to unfolded protein GO:0034620 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.	4	O18805 (/ISS) O35613 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Regulation of apoptotic process GO:0042981 Any process that modulates the occurrence or rate of cell death by apoptotic process.	4	Q5UDQ8 (/IGI) Q8WSS9 (/IGI) Q95TR4 (/IGI) Q9VMD0 (/IGI)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	4	Q5UDQ8 (/IMP) Q8WSS9 (/IMP) Q95TR4 (/IMP) Q9VMD0 (/IMP)
Cellular response to cadmium ion GO:0071276 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	4	O18805 (/ISS) O35613 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Cellular response to copper ion GO:0071280 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.	4	O18805 (/ISS) O35613 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Cellular response to diamide GO:0072738 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.	4	O18805 (/ISS) O35613 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Cellular response to sodium arsenite GO:1903936 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.	4	O18805 (/ISS) O35613 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	3	O35613 (/IDA) Q9UER7 (/IDA) Q9UER7 (/IDA)
Positive regulation of protein phosphorylation GO:0001934 Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.	2	Q9UER7 (/IGI) Q9UER7 (/IGI)
Nucleosome assembly GO:0006334 The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Chromatin remodeling GO:0006338 Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Regulation of transcription, DNA-templated GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Apoptotic process GO:0006915 A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.	2	Q9UER7 (/TAS) Q9UER7 (/TAS)
Activation of JUN kinase activity GO:0007257 The initiation of the activity of the inactive enzyme JUN kinase (JNK).	2	Q9UER7 (/TAS) Q9UER7 (/TAS)
Extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.	2	Q9UER7 (/TAS) Q9UER7 (/TAS)
Androgen receptor signaling pathway GO:0030521 Any series of molecular signals generated as a consequence of an androgen binding to its receptor.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Regulation of protein ubiquitination GO:0031396 Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Cellular response to heat GO:0034605 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Cellular response to unfolded protein GO:0034620 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Positive regulation of protein kinase activity GO:0045860 Any process that activates or increases the frequency, rate or extent of protein kinase activity.	2	Q9UER7 (/IGI) Q9UER7 (/IGI)
Cellular response to cadmium ion GO:0071276 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Cellular response to copper ion GO:0071280 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Cellular response to diamide GO:0072738 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Positive regulation of neuron death GO:1901216 Any process that activates or increases the frequency, rate or extent of neuron death.	2	Q9UER7 (/IGI) Q9UER7 (/IGI)
Cellular response to sodium arsenite GO:1903936 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	1	Q8VIB2 (/IDA)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	1	O35613 (/ISO)
Mitotic cytokinesis GO:0000281 A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.	1	O35613 (/IMP)
Positive regulation of protein phosphorylation GO:0001934 Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.	1	O35613 (/ISO)
Nucleosome assembly GO:0006334 The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.	1	O35613 (/IMP)
Nucleosome assembly GO:0006334 The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.	1	O35613 (/ISO)
Chromatin remodeling GO:0006338 Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.	1	O35613 (/ISO)
Regulation of transcription, DNA-templated GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	1	O35613 (/ISO)
Response to oxidative stress GO:0006979 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.	1	Q9VMD0 (/IGI)
Response to metal ion GO:0010038 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.	1	Q8VIB2 (/IEP)
Negative regulation of myotube differentiation GO:0010832 Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	1	Q8VIB2 (/IDA)
Negative regulation of myotube differentiation GO:0010832 Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.	1	O35613 (/ISO)
Androgen receptor signaling pathway GO:0030521 Any series of molecular signals generated as a consequence of an androgen binding to its receptor.	1	O35613 (/ISO)
Androgen receptor signaling pathway GO:0030521 Any series of molecular signals generated as a consequence of an androgen binding to its receptor.	1	O35613 (/ISS)
PML body organization GO:0030578 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).	1	Q8VIB2 (/IMP)
PML body organization GO:0030578 A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).	1	O35613 (/ISO)
Regulation of protein ubiquitination GO:0031396 Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.	1	O35613 (/ISO)
Positive regulation of histone phosphorylation GO:0033129 Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.	1	Q8VIB2 (/IMP)
Positive regulation of histone phosphorylation GO:0033129 Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.	1	O35613 (/ISO)
Cellular response to heat GO:0034605 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	1	O35613 (/ISO)
Cellular response to unfolded protein GO:0034620 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.	1	O35613 (/ISO)
Regulation of multicellular organism growth GO:0040014 Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.	1	O35613 (/IMP)
Positive regulation of apoptotic process GO:0043065 Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.	1	Q8VIB2 (/IMP)
Positive regulation of apoptotic process GO:0043065 Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.	1	O35613 (/ISO)
Negative regulation of apoptotic process GO:0043066 Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.	1	O35613 (/IMP)
Positive regulation of protein kinase activity GO:0045860 Any process that activates or increases the frequency, rate or extent of protein kinase activity.	1	O35613 (/ISO)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	1	O35613 (/ISO)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	1	O35613 (/IMP)
Protein localization to chromatin GO:0071168 Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.	1	O35613 (/IMP)
Cellular response to cadmium ion GO:0071276 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	1	O35613 (/ISO)
Cellular response to copper ion GO:0071280 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.	1	O35613 (/ISO)
Cellular response to tumor necrosis factor GO:0071356 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.	1	Q8VIB2 (/IEP)
Cellular response to anoxia GO:0071454 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.	1	Q8VIB2 (/IEP)
Cellular response to diamide GO:0072738 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.	1	O35613 (/ISO)
Apoptotic signaling pathway GO:0097190 A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.	1	O35613 (/IGI)
Positive regulation of neuron death GO:1901216 Any process that activates or increases the frequency, rate or extent of neuron death.	1	O35613 (/ISO)
Cellular response to sodium arsenite GO:1903936 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.	1	O35613 (/ISO)
Positive regulation of apoptotic signaling pathway GO:2001235 Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.	1	O35613 (/IDA)
Positive regulation of apoptotic signaling pathway GO:2001235 Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.	1	O35613 (/IGI)

There are 28 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	16	A0A024RCS3 (/IDA) A0A024RCS3 (/IDA) A3KNT2 (/IDA) A7E2H6 (/IDA) F1QQQ8 (/IDA) O18805 (/IDA) O35613 (/IDA) Q1LUU4 (/IDA) Q567Z8 (/IDA) Q6DEL6 (/IDA) (6 more)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	5	O18805 (/ISS) O35613 (/ISS) Q5RAL6 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	5	O18805 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS) Q9UER7 (/ISS) Q9UER7 (/ISS)
Nuclear body GO:0016604 Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.	4	A0A024RCS3 (/IDA) A0A024RCS3 (/IDA) Q9UER7 (/IDA) Q9UER7 (/IDA)
PML body GO:0016605 A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.	4	O35613 (/IDA) Q8VIB2 (/IDA) Q9UER7 (/IDA) Q9UER7 (/IDA)
PML body GO:0016605 A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.	4	O18805 (/ISS) O35613 (/ISS) Q5TJE1 (/ISS) Q8VIB2 (/ISS)
Chromosome, centromeric region GO:0000775 The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.	2	Q9UER7 (/IDA) Q9UER7 (/IDA)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	2	Q9UER7 (/TAS) Q9UER7 (/TAS)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	2	Q9UER7 (/TAS) Q9UER7 (/TAS)
Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	2	O35613 (/IDA) Q9VMD0 (/IDA)
PML body GO:0016605 A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.	2	Q9UER7 (/TAS) Q9UER7 (/TAS)
Chromosome, centromeric region GO:0000775 The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.	1	O35613 (/ISO)
Heterochromatin GO:0000792 A compact and highly condensed form of chromatin.	1	O35613 (/IDA)
XY body GO:0001741 A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.	1	Q8VIB2 (/IDA)
XY body GO:0001741 A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.	1	O35613 (/ISO)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	1	O35613 (/ISO)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	1	Q8VIB2 (/IDA)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	1	O35613 (/ISO)
Microtubule GO:0005874 Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.	1	Q8VIB2 (/IDA)
Microtubule GO:0005874 Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.	1	O35613 (/ISO)
Cell cortex GO:0005938 The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.	1	Q8VIB2 (/IDA)
Cell cortex GO:0005938 The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.	1	O35613 (/ISO)
Nuclear body GO:0016604 Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.	1	O35613 (/ISO)
PML body GO:0016605 A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.	1	O35613 (/ISO)
Neuron projection GO:0043005 A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	1	Q8VIB2 (/IDA)
Neuron projection GO:0043005 A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.	1	O35613 (/ISO)
Cell body GO:0044297 The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.	1	Q8VIB2 (/IDA)
Cell body GO:0044297 The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.	1	O35613 (/ISO)

Functional Families

There are 39 GO terms relating to "molecular function"

There are 69 GO terms relating to "biological process"

There are 28 GO terms relating to "cellular component"