The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
PRONE domain, subdomain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Rop guanine nucleotide exchange factor 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Rho guanyl-nucleotide exchange factor activity GO:0005089
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
2 Q93ZY2 (/IDA) Q93ZY2 (/IDA)
Rho guanyl-nucleotide exchange factor activity GO:0005089
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
2 Q93ZY2 (/IMP) Q93ZY2 (/IMP)
Rho guanyl-nucleotide exchange factor activity GO:0005089
Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
2 F4K295 (/ISS) Q9LZN0 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q93ZY2 (/IPI) Q93ZY2 (/IPI)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pollen tube growth GO:0009860
Growth of pollen via tip extension of the intine wall.
2 Q93ZY2 (/IMP) Q93ZY2 (/IMP)
Regulation of pollen tube growth GO:0080092
Any process that modulates the frequency, rate or extent of pollen tube growth.
2 Q93ZY2 (/IGI) Q93ZY2 (/IGI)
Regulation of auxin polar transport GO:2000012
Any process that modulates the frequency, rate or extent of auxin polar transport.
2 Q93ZY2 (/IMP) Q93ZY2 (/IMP)
Positive regulation of Rho guanyl-nucleotide exchange factor activity GO:2001108
Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
2 Q93ZY2 (/IMP) Q93ZY2 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 Q93ZY2 (/IDA) Q93ZY2 (/IDA) Q9LZN0 (/IDA)
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
2 Q93ZY2 (/IDA) Q93ZY2 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9LZN0 (/IDA)
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