The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4: Spindle midzone component

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
3 P50275 (/IDA) P50275 (/IDA) P50275 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitotic spindle elongation GO:0000022
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
3 P50275 (/IGI) P50275 (/IGI) P50275 (/IGI)
Mitotic spindle elongation GO:0000022
The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
3 P50275 (/IMP) P50275 (/IMP) P50275 (/IMP)
Mitotic spindle pole body separation GO:0000073
The release of duplicated mitotic spindle pole bodies (SPBs) that begins with the nucleation of microtubules from each SPB within the nucleus, leading to V-shaped spindle microtubules. Interpolar microtubules elongate from each pole forming overlapping microtubules. Capture and antiparallel sliding apart promotes initial SPB separation. Following liberation (severing of the half-bridge), SPBs diffuse through the nuclear membrane until they are opposite each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble.
3 P50275 (/IGI) P50275 (/IGI) P50275 (/IGI)
Septum digestion after cytokinesis GO:0000920
The process of physically separating the septal cell wall material by enzymatic digestion, that occurs after daughter cells are separated by cytokinesis.
3 P50275 (/IMP) P50275 (/IMP) P50275 (/IMP)
Microtubule bundle formation GO:0001578
A process that results in a parallel arrangement of microtubules.
3 P50275 (/IDA) P50275 (/IDA) P50275 (/IDA)
Mitotic spindle organization GO:0007052
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
3 P50275 (/IMP) P50275 (/IMP) P50275 (/IMP)
Spindle midzone assembly GO:0051255
The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.
3 P50275 (/IMP) P50275 (/IMP) P50275 (/IMP)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P50275 (/HDA) P50275 (/HDA) P50275 (/HDA)
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
3 P50275 (/IDA) P50275 (/IDA) P50275 (/IDA)
Microtubule GO:0005874
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
3 P50275 (/HDA) P50275 (/HDA) P50275 (/HDA)
Nuclear microtubule GO:0005880
Any microtubule in the nucleus of a cell.
3 P50275 (/IDA) P50275 (/IDA) P50275 (/IDA)
Spindle midzone GO:0051233
The area in the center of the spindle where the spindle microtubules from opposite poles overlap.
3 P50275 (/IDA) P50275 (/IDA) P50275 (/IDA)
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