The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: 65-kDa microtubule-associated protein 6

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
4 F4K3E4 (/IDA) Q9FHM4 (/IDA) Q9FHM4 (/IDA) Q9SIS3 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q9FLP0 (/IPI) Q9FLP0 (/IPI)
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
2 Q9FLP0 (/IPI) Q9FLP0 (/IPI)

There are 13 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytokinesis by cell plate formation GO:0000911
The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana.
3 F4K3E4 (/IMP) Q9FHM4 (/IMP) Q9FHM4 (/IMP)
Microtubule polymerization GO:0046785
The addition of tubulin heterodimers to one or both ends of a microtubule.
3 F4K3E4 (/IDA) Q9FHM4 (/IDA) Q9FHM4 (/IDA)
Post-embryonic root development GO:0048528
The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure.
3 F4K3E4 (/IGI) Q8LEG3 (/IGI) Q8LEG3 (/IGI)
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
2 Q9FHM4 (/IMP) Q9FHM4 (/IMP)
Nuclear division GO:0000280
The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
2 Q9FHM4 (/IMP) Q9FHM4 (/IMP)
Cytokinesis by cell plate formation GO:0000911
The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana.
2 Q8LEG3 (/IGI) Q8LEG3 (/IGI)
Response to nematode GO:0009624
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode.
2 Q9FHM4 (/IMP) Q9FHM4 (/IMP)
Cortical microtubule organization GO:0043622
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell.
2 Q9FLP0 (/IMP) Q9FLP0 (/IMP)
Cell division GO:0051301
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
2 Q8LEG3 (/IGI) Q8LEG3 (/IGI)
Formation by symbiont of syncytium involving giant cell for nutrient acquisition from host GO:0052096
The assembly by an organism of a syncytium, a nematode-induced multi-nucleate and physiologically active aggregation of fused root cells which exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2 Q9FHM4 (/IMP) Q9FHM4 (/IMP)
Microtubule bundle formation GO:0001578
A process that results in a parallel arrangement of microtubules.
1 F4K3E4 (/IDA)
Microtubule nucleation GO:0007020
The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).
1 F4K3E4 (/IDA)
Positive regulation of microtubule polymerization GO:0031116
Any process that activates or increases the frequency, rate or extent of microtubule polymerization.
1 F4K3E4 (/IDA)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Phragmoplast GO:0009524
Fibrous structure (light microscope view) that arises between the daughter nuclei at telophase and within which the initial partition (cell plate), dividing the mother cell in two (cytokinesis), is formed. Appears at first as a spindle connected to the two nuclei, but later spreads laterally in the form of a ring. Consists of microtubules.
7 F4K3E4 (/IDA) Q8LEG3 (/IDA) Q8LEG3 (/IDA) Q9C7G0 (/IDA) Q9FHM4 (/IDA) Q9FHM4 (/IDA) Q9SIS3 (/IDA)
Microtubule GO:0005874
Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
6 F4K3E4 (/IDA) Q8LEG3 (/IDA) Q8LEG3 (/IDA) Q9C7G0 (/IDA) Q9FHM4 (/IDA) Q9FHM4 (/IDA)
Preprophase band GO:0009574
A dense band of microtubules, 1-3 pm wide, that appears just beneath the cell membrane before the start of cell division in the cells of higher plants. It precedes the onset of prophase and then disappears as mitosis begins, yet it somehow determines the plane of orientation of the new cell plate forming in late telophase and marks the zone of the parental cell wall where fusion with the growing cell plate ultimately occurs.
6 F4K3E4 (/IDA) Q8LEG3 (/IDA) Q8LEG3 (/IDA) Q9FHM4 (/IDA) Q9FHM4 (/IDA) Q9SIS3 (/IDA)
Cortical microtubule GO:0055028
Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol.
5 F4K3E4 (/IDA) Q8LEG3 (/IDA) Q8LEG3 (/IDA) Q9FHM4 (/IDA) Q9FHM4 (/IDA)
Spindle GO:0005819
The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
4 F4K3E4 (/IDA) Q8LEG3 (/IDA) Q8LEG3 (/IDA) Q9C7G0 (/IDA)
Mitotic spindle GO:0072686
A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
3 F4K3E4 (/IDA) Q8LEG3 (/IDA) Q8LEG3 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 F4K3E4 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 F4K3E4 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q9SIS3 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 F4K3E4 (/IDA)
Plastid GO:0009536
Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
1 Q9SIS3 (/IDA)
Cortical microtubule, transverse to long axis GO:0010005
Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition.
1 F4K3E4 (/IDA)
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