The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
VpR/VpX protein, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Protein Vpr

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P12520 (/IPI) P12520 (/IPI) P69726 (/IPI)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
RNA-dependent DNA biosynthetic process GO:0006278
A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.
1 P69726 (/TAS)
Induction by virus of host apoptotic process GO:0019051
The set of viral processes that induce an apoptotic process in infected host cells, facilitating release and spread of progeny virions.
1 P69726 (/IDA)
Viral life cycle GO:0019058
A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome.
1 P69726 (/TAS)
Uncoating of virus GO:0019061
The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome.
1 P69726 (/TAS)
Fusion of virus membrane with host plasma membrane GO:0019064
Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
1 P69726 (/TAS)
Virion assembly GO:0019068
A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed.
1 P69726 (/TAS)
Entry into host cell GO:0030260
The invasion by an organism of a cell of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 P69726 (/TAS)
Suppression by virus of G2/M transition of host mitotic cell cycle GO:0039592
Any viral process that decreases the rate or extent of progression from G2 phase to M phase of the host mitotic cell cycle.
1 P69726 (/IDA)
Nuclear transport GO:0051169
The directed movement of substances into, out of, or within the nucleus.
1 P69726 (/TAS)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 P69726 (/IDA)
Interaction with host GO:0051701
An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
1 P69726 (/IPI)
Establishment of integrated proviral latency GO:0075713
A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage.
1 P69726 (/TAS)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Virion GO:0019012
The complete fully infectious extracellular virus particle.
1 P69726 (/IDA)
Host cell nucleus GO:0042025
A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 P69726 (/IDA)
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