The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Single helix bin
".
FunFam 4: ATPase inhibitor A, mitochondrial
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 21 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
ATPase inhibitor activity GO:0042030
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate.
|
17 |
A3KNL5 (/ISS)
F7BK26 (/ISS)
O35143 (/ISS)
P01096 (/ISS)
Q03344 (/ISS)
Q1LYB6 (/ISS)
Q29307 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
(7 more) |
|
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
17 |
A3KNL5 (/ISS)
F7BK26 (/ISS)
O35143 (/ISS)
P01096 (/ISS)
Q03344 (/ISS)
Q1LYB6 (/ISS)
Q29307 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
(7 more) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
16 |
A3KNL5 (/ISS)
F7BK26 (/ISS)
O35143 (/ISS)
Q03344 (/ISS)
Q1LYB6 (/ISS)
Q29307 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
(6 more) |
|
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
|
13 |
O35143 (/ISS)
Q03344 (/ISS)
Q29307 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q9UII2 (/ISS)
Q9UII2 (/ISS)
(3 more) |
|
Angiostatin binding GO:0043532
Interacting selectively and non-covalently with angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis.
|
9 | O35143 (/ISS) P01096 (/ISS) Q03344 (/ISS) Q29307 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) |
|
ATPase inhibitor activity GO:0042030
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate.
|
7 | P01096 (/IDA) Q03344 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) |
|
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
6 | P01096 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) |
|
Enzyme inhibitor activity GO:0004857
Binds to and stops, prevents or reduces the activity of an enzyme.
|
5 | Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
5 | Q9UII2 (/IPI) Q9UII2 (/IPI) Q9UII2 (/IPI) Q9UII2 (/IPI) Q9UII2 (/IPI) |
|
ATPase inhibitor activity GO:0042030
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate.
|
5 | Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
5 | Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) |
|
Angiostatin binding GO:0043532
Interacting selectively and non-covalently with angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis.
|
5 | Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) |
|
Mitochondrial proton-transporting ATP synthase complex binding GO:0140260
Interacting selectively and non-covalently with a mitochondrial proton-transporting ATP synthase complex.
|
5 | Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | O35143 (/IPI) P01096 (/IPI) |
|
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
|
1 | P01096 (/IDA) |
|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
1 | O35143 (/ISO) |
|
ATPase inhibitor activity GO:0042030
Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate.
|
1 | O35143 (/ISO) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P01096 (/IDA) |
|
Angiostatin binding GO:0043532
Interacting selectively and non-covalently with angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis.
|
1 | O35143 (/ISO) |
|
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
1 | O35143 (/ISO) |
|
Mitochondrial proton-transporting ATP synthase complex binding GO:0140260
Interacting selectively and non-covalently with a mitochondrial proton-transporting ATP synthase complex.
|
1 | O35143 (/ISO) |
There are 36 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of hydrolase activity GO:0051346
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
|
17 |
A3KNL5 (/ISS)
F7BK26 (/ISS)
O35143 (/ISS)
P01096 (/ISS)
Q03344 (/ISS)
Q1LYB6 (/ISS)
Q29307 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
(7 more) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
16 |
A3KNL5 (/ISS)
F7BK26 (/ISS)
O35143 (/ISS)
Q03344 (/ISS)
Q1LYB6 (/ISS)
Q29307 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
(6 more) |
|
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
13 |
O35143 (/ISS)
Q03344 (/ISS)
Q29307 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q9UII2 (/ISS)
Q9UII2 (/ISS)
(3 more) |
|
Heme biosynthetic process GO:0006783
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
|
10 | F7BK26 (/ISS) P01096 (/ISS) Q03344 (/ISS) Q1LYB6 (/ISS) Q29307 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) |
|
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
|
10 | F7BK26 (/ISS) P01096 (/ISS) Q03344 (/ISS) Q1LYB6 (/ISS) Q29307 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) |
|
Negative regulation of endothelial cell proliferation GO:0001937
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
|
9 | O35143 (/ISS) P01096 (/ISS) Q03344 (/ISS) Q29307 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) |
|
Heme biosynthetic process GO:0006783
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
|
7 | A3KNL5 (/IMP) O35143 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) |
|
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
|
7 | A3KNL5 (/IMP) O35143 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) |
|
Negative regulation of hydrolase activity GO:0051346
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
|
6 | P01096 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) |
|
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
5 | Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) |
|
Negative regulation of endothelial cell proliferation GO:0001937
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
|
5 | Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) |
|
Generation of precursor metabolites and energy GO:0006091
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
|
5 | Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) |
|
Negative regulation of ATPase activity GO:0032780
Any process that stops or reduces the rate of ATP hydrolysis by an ATPase.
|
5 | Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) |
|
Mitochondrial depolarization GO:0051882
The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.
|
5 | Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) |
|
Positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052
Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
|
5 | Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) |
|
Regulation of protein targeting to mitochondrion GO:1903214
Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion.
|
5 | Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) |
|
Regulation of ATP metabolic process GO:1903578
Any process that modulates the frequency, rate or extent of ATP metabolic process.
|
5 | Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) |
|
Positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization GO:1904925
Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization.
|
5 | Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) Q9UII2 (/IMP) |
|
Negative regulation of endothelial cell proliferation GO:0001937
Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
|
1 | O35143 (/ISO) |
|
Heme biosynthetic process GO:0006783
The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
|
1 | O35143 (/ISO) |
|
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
|
1 | A3KNL5 (/IMP) |
|
Optokinetic behavior GO:0007634
The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus.
|
1 | A3KNL5 (/IMP) |
|
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
|
1 | O35143 (/ISO) |
|
Negative regulation of ATPase activity GO:0032780
Any process that stops or reduces the rate of ATP hydrolysis by an ATPase.
|
1 | O35143 (/ISO) |
|
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
|
1 | Q1LYB6 (/IMP) |
|
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
|
1 | P01096 (/IDA) |
|
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
|
1 | P01096 (/IDA) |
|
Negative regulation of hydrolase activity GO:0051346
Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
|
1 | O35143 (/ISO) |
|
Mitochondrial depolarization GO:0051882
The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.
|
1 | O35143 (/ISO) |
|
Reactive oxygen species metabolic process GO:0072593
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
|
1 | O35143 (/IMP) |
|
Regulation of neuroinflammatory response GO:0150077
Any process that modulates the frequency, rate or extent of neuroinflammatory response.
|
1 | A3KNL5 (/IMP) |
|
Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901030
Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
|
1 | O35143 (/IMP) |
|
Positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052
Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
|
1 | O35143 (/ISO) |
|
Regulation of protein targeting to mitochondrion GO:1903214
Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion.
|
1 | O35143 (/ISO) |
|
Regulation of ATP metabolic process GO:1903578
Any process that modulates the frequency, rate or extent of ATP metabolic process.
|
1 | O35143 (/ISO) |
|
Positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization GO:1904925
Any process that activates or increases the frequency, rate or extent of autophagy of the mitochondrion in response to mitochondrial depolarization.
|
1 | O35143 (/ISO) |
There are 9 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
13 |
O35143 (/ISS)
Q03344 (/ISS)
Q29307 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q5RFJ9 (/ISS)
Q9UII2 (/ISS)
Q9UII2 (/ISS)
(3 more) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
9 | O35143 (/ISS) P01096 (/ISS) Q03344 (/ISS) Q29307 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) Q5RFJ9 (/ISS) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
7 | P01096 (/IDA) Q03344 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
6 | O35143 (/HDA) Q9UII2 (/HDA) Q9UII2 (/HDA) Q9UII2 (/HDA) Q9UII2 (/HDA) Q9UII2 (/HDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
5 | Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) Q9UII2 (/TAS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
5 | Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) Q9UII2 (/IDA) |
|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
1 | O35143 (/ISO) |
|
Mitochondrial proton-transporting ATP synthase complex GO:0005753
A proton-transporting ATP synthase complex found in the mitochondrial membrane.
|
1 | P01096 (/IDA) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | O35143 (/ISO) |
