The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 134: Transcription factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
7 P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
7 P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter in response to iron GO:0010723
Any process that increases the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.
7 P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP)
Negative regulation of chromatin silencing at telomere GO:0031939
Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres.
7 P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
7 P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
7 P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP) P40574 (/IMP)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
7 P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
7 P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA) P40574 (/IDA)
CATH-Gene3D is a Global Biodata Core Resource Learn more...