The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"iswi atpase
".
FunFam 5: ISWI chromatin-remodeling complex ATPase ISW1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
RDNA binding GO:0000182
Interacting selectively and non-covalently with DNA sequences encoding ribosomal RNA.
|
1 | P38144 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P38144 (/IPI) |
|
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | P38144 (/IDA) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P38144 (/IMP) P41877 (/IMP) |
|
Regulation of transcriptional start site selection at RNA polymerase II promoter GO:0001178
Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
|
1 | P38144 (/IGI) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
1 | P38144 (/IMP) |
|
DNA-templated transcription, elongation GO:0006354
The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
|
1 | P38144 (/IDA) |
|
DNA-templated transcription, elongation GO:0006354
The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
|
1 | P38144 (/IMP) |
|
Termination of RNA polymerase I transcription GO:0006363
The process in which the synthesis of an RNA molecule by RNA polymerase I using a DNA template is completed. RNAP I termination requires binding of a terminator protein so specific sequences downstream of the transcription unit.
|
1 | P38144 (/IGI) |
|
Termination of RNA polymerase II transcription GO:0006369
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.
|
1 | P38144 (/IGI) |
|
Sister chromatid cohesion GO:0007062
The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.
|
1 | P38144 (/IMP) |
|
Positive regulation of vulval development GO:0040026
Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
|
1 | P41877 (/IGI) |
|
Regulation of nucleosome density GO:0060303
Any process that modulates the number of nucleosomes in a given region of a chromosome.
|
1 | P38144 (/IGI) |
|
Regulation of nucleosome density GO:0060303
Any process that modulates the number of nucleosomes in a given region of a chromosome.
|
1 | P38144 (/IMP) |
|
Heterochromatin maintenance involved in chromatin silencing GO:0070870
A chromatin organization process that preserves heterochromatin in a stable functional or structural state, and that contributes to chromatin silencing.
|
1 | P38144 (/IGI) |
|
Heterochromatin maintenance involved in chromatin silencing GO:0070870
A chromatin organization process that preserves heterochromatin in a stable functional or structural state, and that contributes to chromatin silencing.
|
1 | P38144 (/IMP) |
|
Negative regulation of histone exchange GO:1900050
Any process that stops, prevents or reduces the frequency, rate or extent of histone exchange.
|
1 | P38144 (/IMP) |
|
Regulation of chromatin organization GO:1902275
Any process that modulates the frequency, rate or extent of chromatin organization.
|
1 | P38144 (/IMP) |
There are 5 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | P41877 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P38144 (/HDA) |
|
Nucleolar chromatin GO:0030874
The portion of nuclear chromatin associated with the nucleolus; includes the DNA encoding the ribosomal RNA.
|
1 | P38144 (/IDA) |
|
Isw1a complex GO:0036436
An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc3p.
|
1 | P38144 (/IDA) |
|
Isw1b complex GO:0036437
An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc2p and Ioc4p.
|
1 | P38144 (/IDA) |
