The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 95: TOMosyn synaptic protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of presynaptic dense core granule exocytosis GO:0099161
Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis.
8 A0A0K3AR90 (/IDA) A0A0K3ATN9 (/IDA) A0A0K3AWL6 (/IDA) A8WFN4 (/IDA) G5EE26 (/IDA) Q14DX2 (/IDA) Q49HI2 (/IDA) Q49HI3 (/IDA)
Regulation of presynaptic dense core granule exocytosis GO:0099161
Any process that modulates the frequency, rate or extent of presynaptic dense core granule exocytosis.
8 A0A0K3AR90 (/IMP) A0A0K3ATN9 (/IMP) A0A0K3AWL6 (/IMP) A8WFN4 (/IMP) G5EE26 (/IMP) Q14DX2 (/IMP) Q49HI2 (/IMP) Q49HI3 (/IMP)
Regulation of synaptic vesicle priming GO:0010807
Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
7 A0A0K3AR90 (/IDA) A0A0K3ATN9 (/IDA) A0A0K3AWL6 (/IDA) A8WFN4 (/IDA) G5EE26 (/IDA) Q14DX2 (/IDA) Q49HI3 (/IDA)
Regulation of synaptic vesicle priming GO:0010807
Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
7 A0A0K3AR90 (/IMP) A0A0K3ATN9 (/IMP) A0A0K3AWL6 (/IMP) A8WFN4 (/IMP) G5EE26 (/IMP) Q14DX2 (/IMP) Q49HI3 (/IMP)
Regulation of synaptic vesicle docking GO:0099148
Any process that modulates the frequency, rate or extent of synaptic vesicle docking.
7 A0A0K3AR90 (/IDA) A0A0K3ATN9 (/IDA) A0A0K3AWL6 (/IDA) A8WFN4 (/IDA) G5EE26 (/IDA) Q14DX2 (/IDA) Q49HI3 (/IDA)
Regulation of synaptic vesicle docking GO:0099148
Any process that modulates the frequency, rate or extent of synaptic vesicle docking.
7 A0A0K3AR90 (/IMP) A0A0K3ATN9 (/IMP) A0A0K3AWL6 (/IMP) A8WFN4 (/IMP) G5EE26 (/IMP) Q14DX2 (/IMP) Q49HI3 (/IMP)
Synaptic vesicle priming GO:0016082
A process that converts synaptic vesicles to a state of competence for calcium triggered fusion with the active zone membrane by bringing the two membranes into very close proximity. Priming typically (but not always) occurs after docking (Jahn and Fasshauer, 2012). Primed vesicles are also capable of spontaneously fusing with the active zone membrane.
5 A8WFN4 (/IMP) G5EE26 (/IMP) Q14DX2 (/IMP) Q49HI2 (/IMP) Q49HI3 (/IMP)
Cellular response to salt GO:1902075
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.
1 A0A0K3ATN9 (/IGI)
Cellular response to salt GO:1902075
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.
1 A0A0K3ATN9 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
8 A0A0K3AR90 (/IDA) A0A0K3ATN9 (/IDA) A0A0K3AWL6 (/IDA) A8WFN4 (/IDA) G5EE26 (/IDA) Q14DX2 (/IDA) Q49HI2 (/IDA) Q49HI3 (/IDA)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
8 A0A0K3AR90 (/IMP) A0A0K3ATN9 (/IMP) A0A0K3AWL6 (/IMP) A8WFN4 (/IMP) G5EE26 (/IMP) Q14DX2 (/IMP) Q49HI2 (/IMP) Q49HI3 (/IMP)
Extrinsic component of neuronal dense core vesicle membrane GO:0098674
The component of the neuronal dense core vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
7 A0A0K3AR90 (/IDA) A0A0K3ATN9 (/IDA) A0A0K3AWL6 (/IDA) A8WFN4 (/IDA) G5EE26 (/IDA) Q14DX2 (/IDA) Q49HI3 (/IDA)
Cholinergic synapse GO:0098981
A synapse that uses acetylcholine as a neurotransmitter.
7 A0A0K3AR90 (/IDA) A0A0K3ATN9 (/IDA) A0A0K3AWL6 (/IDA) A8WFN4 (/IDA) G5EE26 (/IDA) Q14DX2 (/IDA) Q49HI3 (/IDA)
Cholinergic synapse GO:0098981
A synapse that uses acetylcholine as a neurotransmitter.
7 A0A0K3AR90 (/IMP) A0A0K3ATN9 (/IMP) A0A0K3AWL6 (/IMP) A8WFN4 (/IMP) G5EE26 (/IMP) Q14DX2 (/IMP) Q49HI3 (/IMP)
GABA-ergic synapse GO:0098982
A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
7 A0A0K3AR90 (/IDA) A0A0K3ATN9 (/IDA) A0A0K3AWL6 (/IDA) A8WFN4 (/IDA) G5EE26 (/IDA) Q14DX2 (/IDA) Q49HI3 (/IDA)
GABA-ergic synapse GO:0098982
A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
7 A0A0K3AR90 (/IMP) A0A0K3ATN9 (/IMP) A0A0K3AWL6 (/IMP) A8WFN4 (/IMP) G5EE26 (/IMP) Q14DX2 (/IMP) Q49HI3 (/IMP)
SNARE complex GO:0031201
A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25.
5 A8WFN4 (/IPI) G5EE26 (/IPI) Q14DX2 (/IPI) Q49HI2 (/IPI) Q49HI3 (/IPI)
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