The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15: Syntaxin-18, putative

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
6 Q68FW4 (/IPI) Q9P2W9 (/IPI) Q9P2W9 (/IPI) Q9P2W9 (/IPI) Q9P2W9 (/IPI) Q9P2W9 (/IPI)
SNARE binding GO:0000149
Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
1 Q9VC58 (/ISS)
SNAP receptor activity GO:0005484
Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
1 Q9VC58 (/ISS)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 Q8VDS8 (/IPI)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0006890
The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.
5 Q9P2W9 (/TAS) Q9P2W9 (/TAS) Q9P2W9 (/TAS) Q9P2W9 (/TAS) Q9P2W9 (/TAS)
Endoplasmic reticulum membrane organization GO:0090158
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane.
5 Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP)
Positive regulation of organelle assembly GO:1902117
Any process that activates or increases the frequency, rate or extent of organelle assembly.
5 Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP)
Positive regulation of ER to Golgi vesicle-mediated transport GO:1902953
Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.
5 Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP)
Regulation of Golgi organization GO:1903358
Any process that modulates the frequency, rate or extent of Golgi organization.
5 Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP) Q9P2W9 (/IMP)
Neuromuscular synaptic transmission GO:0007274
The process of synaptic transmission from a neuron to a muscle, across a synapse.
1 Q9VC58 (/IMP)
Neuromuscular junction development GO:0007528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
1 Q9VC58 (/IMP)
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
1 Q9VC58 (/ISS)
Endoplasmic reticulum membrane organization GO:0090158
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane.
1 Q8VDS8 (/ISO)
Positive regulation of organelle assembly GO:1902117
Any process that activates or increases the frequency, rate or extent of organelle assembly.
1 Q8VDS8 (/ISO)
Positive regulation of ER to Golgi vesicle-mediated transport GO:1902953
Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.
1 Q8VDS8 (/ISO)
Regulation of Golgi organization GO:1903358
Any process that modulates the frequency, rate or extent of Golgi organization.
1 Q8VDS8 (/ISO)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
5 Q9P2W9 (/IDA) Q9P2W9 (/IDA) Q9P2W9 (/IDA) Q9P2W9 (/IDA) Q9P2W9 (/IDA)
Endoplasmic reticulum membrane GO:0005789
The lipid bilayer surrounding the endoplasmic reticulum.
5 Q9P2W9 (/TAS) Q9P2W9 (/TAS) Q9P2W9 (/TAS) Q9P2W9 (/TAS) Q9P2W9 (/TAS)
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
1 Q8VDS8 (/ISO)
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
1 Q9VC58 (/IDA)
SNARE complex GO:0031201
A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25.
1 Q9VC58 (/ISS)
Neuromuscular junction GO:0031594
The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
1 Q9VC58 (/IDA)
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