CATH Superfamily 1.20.5.110
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 12: Mitofusin 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | O95140 (/IPI) Q80U63 (/IPI) Q811U4 (/IPI) Q8IWA4 (/IPI) |
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
3 | Q7YU24 (/ISS) Q811U4 (/ISS) Q8R4Z9 (/ISS) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q8R4Z9 (/IDA) Q8R500 (/IDA) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
2 | Q80U63 (/ISO) Q811U4 (/ISO) |
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | Q8IWA4 (/IDA) |
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | Q8IWA4 (/IMP) |
GTPase activity GO:0003924
Catalysis of the reaction: GTP + H2O = GDP + phosphate.
|
1 | Q811U4 (/ISO) |
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
|
1 | Q8R500 (/IMP) |
GTP binding GO:0005525
Interacting selectively and non-covalently with GTP, guanosine triphosphate.
|
1 | Q80U63 (/ISO) |
Ras GTPase binding GO:0017016
Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases.
|
1 | Q8R500 (/IDA) |
Ras GTPase binding GO:0017016
Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases.
|
1 | Q80U63 (/ISO) |
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | O95140 (/IPI) |
Ubiquitin protein ligase binding GO:0031625
Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
|
1 | Q80U63 (/ISO) |
Proteoglycan binding GO:0043394
Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
|
1 | Q8R500 (/IPI) |
Proteoglycan binding GO:0043394
Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
|
1 | Q80U63 (/ISO) |
GTPase binding GO:0051020
Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q8R500 (/IDA) |
GTPase binding GO:0051020
Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q8R500 (/IPI) |
GTPase binding GO:0051020
Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
|
1 | Q80U63 (/ISO) |
There are 113 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitochondrial fusion GO:0008053
Merging of two or more mitochondria within a cell to form a single compartment.
|
6 | O95140 (/IMP) Q7YU24 (/IMP) Q80U63 (/IMP) Q811U4 (/IMP) Q8IWA4 (/IMP) Q8R500 (/IMP) |
Mitochondrion localization GO:0051646
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
|
5 | Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) Q811U4 (/ISS) Q8R4Z9 (/ISS) |
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
|
4 | Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) Q8R500 (/ISS) |
Mitochondrial membrane organization GO:0007006
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
|
4 | Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) Q8R500 (/ISS) |
Mitochondrial fusion GO:0008053
Merging of two or more mitochondria within a cell to form a single compartment.
|
4 | O95140 (/ISS) Q7YU24 (/ISS) Q8R4Z9 (/ISS) Q8R500 (/ISS) |
Negative regulation of smooth muscle cell proliferation GO:0048662
Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
|
4 | O95140 (/ISS) Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) |
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
|
4 | F7FHF7 (/ISS) O95140 (/ISS) Q6IRL2 (/ISS) Q8R500 (/ISS) |
Mitochondrion morphogenesis GO:0070584
The process in which the anatomical structures of a mitochondrion are generated and organized.
|
3 | Q7YU24 (/IMP) Q8R4Z9 (/IMP) Q8R500 (/IMP) |
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
|
2 | Q7YU24 (/IMP) Q8R500 (/IMP) |
Mitochondrial fusion GO:0008053
Merging of two or more mitochondria within a cell to form a single compartment.
|
2 | Q80U63 (/ISO) Q811U4 (/ISO) |
Male gonad development GO:0008584
The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
|
2 | Q8R4Z9 (/IEP) Q8R500 (/IEP) |
Positive regulation of mitochondrial fusion GO:0010636
Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
|
2 | Q7YU24 (/IMP) Q8R4Z9 (/IMP) |
Response to muscle activity GO:0014850
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.
|
2 | Q8R4Z9 (/IEP) Q8R500 (/IEP) |
Macroautophagy GO:0016236
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Some types of macroautophagy, e.g. pexophagy, mitophagy, involve selective targeting of the targets to be degraded.
|
2 | O95140 (/TAS) Q8IWA4 (/TAS) |
Axonal transport of mitochondrion GO:0019896
The directed movement of mitochondria along microtubules in nerve cell axons.
|
2 | A8WIN6 (/IMP) Q7YU24 (/IMP) |
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
|
2 | Q8R4Z9 (/IEP) Q8R500 (/IEP) |
GTP metabolic process GO:0046039
The chemical reactions and pathways involving GTP, guanosine triphosphate.
|
2 | Q811U4 (/ISS) Q8R4Z9 (/ISS) |
Intracellular distribution of mitochondria GO:0048312
Any process that establishes the spatial arrangement of mitochondria within the cell.
|
2 | Q8R4Z9 (/IMP) Q8R500 (/IMP) |
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
2 | Q8R4Z9 (/IEP) Q8R500 (/IEP) |
Response to electrical stimulus GO:0051602
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.
|
2 | Q8R4Z9 (/IEP) Q8R500 (/IEP) |
Mitochondrion localization GO:0051646
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
|
2 | Q80U63 (/ISO) Q811U4 (/ISO) |
Positive regulation of dendritic spine morphogenesis GO:0061003
Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
2 | Q8R4Z9 (/IMP) Q8R500 (/IMP) |
Cellular response to glucose stimulus GO:0071333
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
|
2 | Q8R4Z9 (/IEP) Q8R500 (/IEP) |
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
2 | Q8R4Z9 (/IEP) Q8R500 (/IEP) |
Cellular response to dexamethasone stimulus GO:0071549
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
|
2 | Q8R4Z9 (/IEP) Q8R500 (/IEP) |
Negative regulation of mitochondrial fission GO:0090258
Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
|
2 | Q8R4Z9 (/IMP) Q8R500 (/IMP) |
Cellular response to oxygen-glucose deprivation GO:0090650
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.
|
2 | Q8R4Z9 (/IEP) Q8R500 (/IEP) |
Response to flavonoid GO:1905395
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.
|
2 | Q8R4Z9 (/IEP) Q8R500 (/IEP) |
Mitochondrial membrane fusion GO:1990613
The joining of two lipid bilayers that surround the mitochondria.
|
2 | Q811U4 (/ISS) Q8R4Z9 (/ISS) |
Response to hypobaric hypoxia GO:1990910
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level).
|
2 | Q8R4Z9 (/IEP) Q8R500 (/IEP) |
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
1 | Q8R500 (/IEP) |
Blastocyst formation GO:0001825
The initial formation of a blastocyst from a solid ball of cells known as a morula.
|
1 | Q80U63 (/IMP) |
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
|
1 | O95140 (/IDA) |
Protein targeting to mitochondrion GO:0006626
The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
|
1 | Q80U63 (/ISO) |
Ecdysone biosynthetic process GO:0006697
The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.
|
1 | Q7YU24 (/IMP) |
Mitochondrial membrane organization GO:0007006
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
|
1 | O95140 (/IDA) |
Mitochondrial membrane organization GO:0007006
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
|
1 | Q80U63 (/ISO) |
Endoplasmic reticulum organization GO:0007029
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
|
1 | Q7YU24 (/IMP) |
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | Q8R500 (/IEP) |
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
|
1 | A8WIN6 (/IMP) |
Neuromuscular junction development GO:0007528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
|
1 | A8WIN6 (/IMP) |
Blood coagulation GO:0007596
The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
|
1 | O95140 (/TAS) |
Mitochondrial fusion GO:0008053
Merging of two or more mitochondria within a cell to form a single compartment.
|
1 | Q8IWA4 (/IDA) |
Mitochondrial fusion GO:0008053
Merging of two or more mitochondria within a cell to form a single compartment.
|
1 | O95140 (/NAS) |
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
1 | Q8R500 (/IMP) |
Adult locomotory behavior GO:0008344
Locomotory behavior in a fully developed and mature organism.
|
1 | Q7YU24 (/IMP) |
Response to manganese ion GO:0010042
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
|
1 | Q8R4Z9 (/IEP) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q8R500 (/IMP) |
Positive regulation of mitochondrial fusion GO:0010636
Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
|
1 | Q811U4 (/ISO) |
Negative regulation of cardiac muscle cell apoptotic process GO:0010667
Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
|
1 | Q8R500 (/IMP) |
Positive regulation of hydrogen peroxide biosynthetic process GO:0010729
Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
|
1 | Q8R500 (/IMP) |
Positive regulation of mitochondrial membrane potential GO:0010918
Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
|
1 | Q8R500 (/IMP) |
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
|
1 | A8WIN6 (/IMP) |
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
|
1 | Q8R500 (/IEP) |
Lipid droplet organization GO:0034389
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.
|
1 | Q7YU24 (/IMP) |
Protein localization to phagophore assembly site GO:0034497
Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS).
|
1 | O95140 (/IDA) |
Protein localization to phagophore assembly site GO:0034497
Any process in which a protein is transported to, or maintained at, the phagophore assembly site (PAS).
|
1 | Q80U63 (/ISO) |
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
|
1 | Q7YU24 (/IMP) |
Positive regulation of chromatin binding GO:0035563
Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
1 | Q8R500 (/IMP) |
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
|
1 | Q8R4Z9 (/IEP) |
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
|
1 | Q8R500 (/IMP) |
Negative regulation of cell size GO:0045792
Any process that reduces cell size.
|
1 | Q8R500 (/IMP) |
GTP metabolic process GO:0046039
The chemical reactions and pathways involving GTP, guanosine triphosphate.
|
1 | Q8IWA4 (/IDA) |
GTP metabolic process GO:0046039
The chemical reactions and pathways involving GTP, guanosine triphosphate.
|
1 | Q811U4 (/ISO) |
Positive regulation of glucose import GO:0046326
Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
|
1 | Q8R500 (/IMP) |
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
|
1 | O95140 (/IDA) |
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
|
1 | Q80U63 (/ISO) |
Positive regulation of insulin receptor signaling pathway GO:0046628
Any process that increases the frequency, rate or extent of insulin receptor signaling.
|
1 | Q8R500 (/IMP) |
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
|
1 | Q8R500 (/IEP) |
Intracellular distribution of mitochondria GO:0048312
Any process that establishes the spatial arrangement of mitochondria within the cell.
|
1 | Q811U4 (/ISO) |
Camera-type eye morphogenesis GO:0048593
The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
|
1 | Q80U63 (/IMP) |
Negative regulation of smooth muscle cell proliferation GO:0048662
Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
|
1 | Q8R500 (/IDA) |
Response to axon injury GO:0048678
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.
|
1 | Q8R500 (/IEP) |
Response to corticosterone GO:0051412
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
|
1 | Q8R4Z9 (/IEP) |
Mitochondrial calcium ion homeostasis GO:0051560
Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.
|
1 | Q8R500 (/IMP) |
Mitochondrion localization GO:0051646
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
|
1 | O95140 (/IDA) |
Mitochondrion localization GO:0051646
Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
|
1 | Q8IWA4 (/IMP) |
Negative regulation of glial cell proliferation GO:0060253
Any process that stops or decreases the rate or extent of glial cell proliferation.
|
1 | Q8R500 (/IMP) |
Negative regulation of sarcomere organization GO:0060299
Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
|
1 | Q8R500 (/IMP) |
Negative regulation of cell death GO:0060548
Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
|
1 | Q8R500 (/IMP) |
Positive regulation of dendritic spine morphogenesis GO:0061003
Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
|
1 | Q811U4 (/ISO) |
Parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization GO:0061734
A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule.
|
1 | Q80U63 (/IMP) |
Parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization GO:0061734
A positive regulation of the macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule.
|
1 | O95140 (/ISS) |
Response to fatty acid GO:0070542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
|
1 | Q8R500 (/IEP) |
Mitochondrion morphogenesis GO:0070584
The process in which the anatomical structures of a mitochondrion are generated and organized.
|
1 | Q811U4 (/ISO) |
Cellular response to manganese ion GO:0071287
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
|
1 | Q8R500 (/IEP) |
Cellular response to testosterone stimulus GO:0071394
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
|
1 | Q8R500 (/IEP) |
Cellular response to low-density lipoprotein particle stimulus GO:0071404
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.
|
1 | Q8R500 (/IEP) |
Cellular response to ionizing radiation GO:0071479
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
|
1 | Q8R500 (/IEP) |
Mitotic cell cycle arrest GO:0071850
The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M).
|
1 | Q8R500 (/IDA) |
Cellular response to mercaptoethanol GO:0072705
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.
|
1 | Q8R500 (/IEP) |
Regulation of mitochondrial fission GO:0090140
Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
|
1 | Q7YU24 (/IMP) |
Negative regulation of release of cytochrome c from mitochondria GO:0090201
Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
|
1 | Q8R500 (/IMP) |
Negative regulation of mitochondrial fission GO:0090258
Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
|
1 | Q811U4 (/ISO) |
Positive regulation of cold-induced thermogenesis GO:0120162
Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.
|
1 | Q80U63 (/IMP) |
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
|
1 | Q8R500 (/IMP) |
Positive regulation of cellular respiration GO:1901857
Any process that activates or increases the frequency, rate or extent of cellular respiration.
|
1 | Q8R500 (/IMP) |
Response to fluoride GO:1902617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.
|
1 | Q8R4Z9 (/IEP) |
Negative regulation of reactive oxygen species biosynthetic process GO:1903427
Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process.
|
1 | Q8R500 (/IMP) |
Positive regulation of reactive oxygen species biosynthetic process GO:1903428
Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process.
|
1 | Q8R500 (/IMP) |
Response to L-arginine GO:1903576
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.
|
1 | Q8R500 (/IEP) |
Negative regulation of vascular smooth muscle cell proliferation GO:1904706
Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.
|
1 | Q8R500 (/IMP) |
Positive regulation of vascular smooth muscle cell proliferation GO:1904707
Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.
|
1 | O95140 (/IMP) |
Positive regulation of vascular smooth muscle cell proliferation GO:1904707
Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.
|
1 | Q80U63 (/ISO) |
Cellular response to L-glutamate GO:1905232
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus.
|
1 | Q8R500 (/IEP) |
Response to D-galactose GO:1905377
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus.
|
1 | Q8R500 (/IEP) |
Positive regulation of vascular associated smooth muscle cell apoptotic process GO:1905461
Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.
|
1 | O95140 (/IMP) |
Positive regulation of vascular associated smooth muscle cell apoptotic process GO:1905461
Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.
|
1 | Q80U63 (/ISO) |
Mitochondrial membrane fusion GO:1990613
The joining of two lipid bilayers that surround the mitochondria.
|
1 | Q8IWA4 (/IMP) |
Mitochondrial membrane fusion GO:1990613
The joining of two lipid bilayers that surround the mitochondria.
|
1 | Q811U4 (/ISO) |
Positive regulation of ovarian follicle development GO:2000386
Any process that activates or increases the frequency, rate or extent of ovarian follicle development.
|
1 | Q8R500 (/IMP) |
Positive regulation of estradiol secretion GO:2000866
Any process that activates or increases the frequency, rate or extent of estradiol secretion.
|
1 | Q8R500 (/IMP) |
Positive regulation of progesterone secretion GO:2000872
Any process that activates or increases the frequency, rate or extent of progesterone secretion.
|
1 | Q8R500 (/IMP) |
There are 26 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
4 | O95140 (/IDA) Q80U63 (/IDA) Q8IWA4 (/IDA) Q8R500 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | O95140 (/ISS) Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) |
Intrinsic component of mitochondrial outer membrane GO:0031306
The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
4 | O95140 (/ISS) Q4R5A0 (/ISS) Q5RAE9 (/ISS) Q80U63 (/ISS) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q80U63 (/HDA) Q811U4 (/HDA) |
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
|
2 | Q80U63 (/ISO) Q811U4 (/ISO) |
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
|
2 | Q8R4Z9 (/IDA) Q8R500 (/IDA) |
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
|
2 | Q80U63 (/ISO) Q811U4 (/ISO) |
Mitochondrial outer membrane GO:0005741
The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
|
2 | O95140 (/TAS) Q8IWA4 (/TAS) |
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | Q811U4 (/ISS) Q8R4Z9 (/ISS) |
Outer mitochondrial membrane protein complex GO:0098799
Any protein complex that is part of the outer mitochondrial membrane.
|
2 | Q811U4 (/ISS) Q8R4Z9 (/ISS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8R500 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q80U63 (/ISO) |
Mitochondrial envelope GO:0005740
The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
|
1 | Q7YU24 (/ISS) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q8R4Z9 (/IDA) |
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
|
1 | Q811U4 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8R500 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q80U63 (/ISO) |
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
|
1 | Q80U63 (/IDA) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q8IWA4 (/IDA) |
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q811U4 (/ISO) |
Intrinsic component of mitochondrial outer membrane GO:0031306
The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
1 | Q8R500 (/IDA) |
Intrinsic component of mitochondrial outer membrane GO:0031306
The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
1 | Q80U63 (/ISO) |
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q8IWA4 (/IDA) |
Integral component of mitochondrial outer membrane GO:0031307
The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q811U4 (/ISO) |
Outer mitochondrial membrane protein complex GO:0098799
Any protein complex that is part of the outer mitochondrial membrane.
|
1 | Q8IWA4 (/IDA) |
Outer mitochondrial membrane protein complex GO:0098799
Any protein complex that is part of the outer mitochondrial membrane.
|
1 | Q811U4 (/ISO) |