The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Amino acid/polyamine transporter I
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 41: Amino acid permease, putative

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Polyamine transmembrane transporter activity GO:0015203
Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other.
9 Q6Z8D0 (/IDA) Q6Z8D0 (/IDA) Q9C6S4 (/IDA) Q9C6S5 (/IDA) Q9FFL1 (/IDA) Q9LH39 (/IDA) Q9LH39 (/IDA) Q9LHN7 (/IDA) Q9LHN7 (/IDA)
Polyamine transmembrane transporter activity GO:0015203
Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of a membrane to the other.
7 Q9C6S4 (/IGI) Q9C6S5 (/IGI) Q9FFL1 (/IGI) Q9LH39 (/IGI) Q9LH39 (/IGI) Q9LHN7 (/IGI) Q9LHN7 (/IGI)
Amine transmembrane transporter activity GO:0005275
Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
2 Q385A1 (/ISM) Q385A1 (/ISM)
Carbohydrate:proton symporter activity GO:0005351
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + H+(out) = sugar(in) + H+(in).
2 Q38DX8 (/ISM) Q38DX8 (/ISM)
Putrescine transmembrane transporter activity GO:0015489
Enables the transfer of putrescine from one side of a membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
1 Q5C8V6 (/IDA)
Spermidine transmembrane transporter activity GO:0015606
Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other.
1 Q5C8V6 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Polyamine transport GO:0015846
The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
9 Q6Z8D0 (/IDA) Q6Z8D0 (/IDA) Q9C6S4 (/IDA) Q9C6S5 (/IDA) Q9FFL1 (/IDA) Q9LH39 (/IDA) Q9LH39 (/IDA) Q9LHN7 (/IDA) Q9LHN7 (/IDA)
Amino acid transport GO:0006865
The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
4 Q385A1 (/ISM) Q385A1 (/ISM) Q38DX8 (/ISM) Q38DX8 (/ISM)
Phosphoenolpyruvate-dependent sugar phosphotransferase system GO:0009401
The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
2 Q38DX8 (/ISM) Q38DX8 (/ISM)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q9FFL1 (/IMP)
Cadaverine transport GO:0015839
The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q9FFL1 (/IMP)
Putrescine transport GO:0015847
The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
1 Q5C8V6 (/IDA)
Spermine transmembrane transport GO:1903710
The process in which spermine is transported across a membrane.
1 Q5C8V6 (/IDA)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 Q385A1 (/IDA) Q385A1 (/IDA) Q38DX8 (/IDA) Q38DX8 (/IDA)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
2 Q38DX8 (/IDA) Q38DX8 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q5C8V6 (/IDA) Q9FFL1 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
2 Q38DX8 (/ISM) Q38DX8 (/ISM)
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
1 E9AFR8 (/ISO)
Acidocalcisome GO:0020022
An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.
1 E9AFR8 (/ISO)