The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Sodium/glucose cotransporter
".
FunFam 5: sodium/glucose cotransporter 1 isoform X1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Carbohydrate:cation symporter activity GO:0005402
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in).
|
5 | A0PJT9 (/IDA) Q2VPB3 (/IDA) Q3UNC8 (/IDA) Q91ZP4 (/IDA) Q9ET36 (/IDA) |
|
Glucose:sodium symporter activity GO:0005412
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
|
2 | P13866 (/IDA) P53790 (/IDA) |
|
Glucose:sodium symporter activity GO:0005412
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
|
2 | P13866 (/TAS) P53790 (/TAS) |
|
Proton transmembrane transporter activity GO:0015078
Enables the transfer of a proton from one side of a membrane to the other.
|
2 | D3ZIS0 (/IDA) Q9ET37 (/IDA) |
|
Glucose transmembrane transporter activity GO:0005355
Enables the transfer of the hexose monosaccharide glucose from one side of a membrane to the other.
|
1 | Q8C3K6 (/IMP) |
|
Glucose:sodium symporter activity GO:0005412
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
|
1 | Q8C3K6 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P13866 (/IPI) |
|
Proton transmembrane transporter activity GO:0015078
Enables the transfer of a proton from one side of a membrane to the other.
|
1 | Q9ET37 (/ISO) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
|
6 | A0PJT9 (/IDA) P13866 (/IDA) Q2VPB3 (/IDA) Q3UNC8 (/IDA) Q91ZP4 (/IDA) Q9ET36 (/IDA) |
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
5 | A0PJT9 (/IDA) Q2VPB3 (/IDA) Q3UNC8 (/IDA) Q91ZP4 (/IDA) Q9ET36 (/IDA) |
|
Carbohydrate transport GO:0008643
The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.
|
5 | A0PJT9 (/IDA) Q2VPB3 (/IDA) Q3UNC8 (/IDA) Q91ZP4 (/IDA) Q9ET36 (/IDA) |
|
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
|
2 | D3ZIS0 (/IDA) Q9ET37 (/IDA) |
|
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
|
2 | P13866 (/IMP) Q8C3K6 (/IMP) |
|
Metanephros development GO:0001656
The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
|
1 | Q8C3K6 (/IMP) |
|
Intestinal D-glucose absorption GO:0001951
Uptake of D-glucose into the blood by absorption from the small intestine.
|
1 | P53790 (/TAS) |
|
Intestinal absorption GO:0050892
Any process in which nutrients are taken up from the contents of the intestine.
|
1 | Q8C3K6 (/IDA) |
|
Intestinal absorption GO:0050892
Any process in which nutrients are taken up from the contents of the intestine.
|
1 | P53790 (/TAS) |
|
Intestinal hexose absorption GO:0106001
Uptake of hexoses, notably D-glucose, fructose, and galactose, into the blood by absorption from the small intestine.
|
1 | P13866 (/TAS) |
|
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
|
1 | Q9ET37 (/ISO) |
|
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
|
1 | Q8C3K6 (/ISO) |
|
Glucose transmembrane transport GO:1904659
The process in which glucose is transported across a membrane.
|
1 | P53790 (/TAS) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
6 | A0PJT9 (/IC) Q2VPB3 (/IC) Q3UNC8 (/IC) Q91ZP4 (/IC) Q9ET36 (/IC) Q9ET37 (/IC) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
2 | P53790 (/IDA) Q8C3K6 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P13866 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P13866 (/TAS) |
|
Brush border GO:0005903
The dense covering of microvilli on the apical surface of a epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
|
1 | Q8C3K6 (/IDA) |
|
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
1 | P53790 (/IDA) |
|
Cell-cell junction GO:0005911
A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
|
1 | Q8C3K6 (/ISO) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | Q8C3K6 (/ISO) |
|
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
|
1 | P53790 (/IDA) |
|
Brush border membrane GO:0031526
The portion of the plasma membrane surrounding the brush border.
|
1 | Q8C3K6 (/ISO) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | P13866 (/HDA) |