The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Multidrug resistance protein D
".
FunFam 22: MFS drug transporter, putative
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Basic amino acid transmembrane transporter activity GO:0015174
Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7.
|
3 | P38358 (/IDA) P38358 (/IDA) P38358 (/IDA) |
|
Basic amino acid transmembrane transporter activity GO:0015174
Enables the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7.
|
3 | P38358 (/IMP) P38358 (/IMP) P38358 (/IMP) |
|
L-amino acid transmembrane transporter activity GO:0015179
Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.
|
1 | B5BP47 (/ISS) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Basic amino acid transport GO:0015802
The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | P38358 (/IMP) P38358 (/IMP) P38358 (/IMP) |
|
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
|
3 | P38358 (/IDA) P38358 (/IDA) P38358 (/IDA) |
|
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
|
3 | P38358 (/IMP) P38358 (/IMP) P38358 (/IMP) |
|
L-histidine transmembrane import into vacuole GO:0090513
The directed movement of L-histidine into the vacuole across the vacuolar membrane.
|
1 | B5BP47 (/IMP) |
|
L-lysine transmembrane import into vacuole GO:0090517
The directed movement of L-lysine into the vacuole across the vacuolar membrane.
|
1 | B5BP47 (/IMP) |
|
L-arginine transmembrane import into vacuole GO:0090518
The directed movement of L-arginine into the vacuole across the vacuolar membrane.
|
1 | B5BP47 (/IMP) |
|
L-valine transmembrane import into vacuole GO:0110101
The directed movement of L-valine into the vacuole across the vacuolar membrane.
|
1 | B5BP47 (/IMP) |
|
Asparagine transmembrane import into vacuole GO:1990591
The directed movement of asparagine into the vacuole across the vacuolar membrane.
|
1 | B5BP47 (/IMP) |
There are 3 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
|
4 | B5BP47 (/IDA) P38358 (/IDA) P38358 (/IDA) P38358 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
3 | P38358 (/HDA) P38358 (/HDA) P38358 (/HDA) |
|
Integral component of fungal-type vacuolar membrane GO:0071627
The component of the fungal-type vacuole membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | B5BP47 (/ISS) |