The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"V-type ATP synthase subunit C domain
".
FunFam 3: V-type proton ATPase subunit
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
14 |
P32366 (/IPI)
P32366 (/IPI)
P32366 (/IPI)
P32366 (/IPI)
P32366 (/IPI)
P32366 (/IPI)
P32366 (/IPI)
P32366 (/IPI)
P32366 (/IPI)
P54641 (/IPI)
(4 more) |
|
Proton-transporting ATPase activity, rotational mechanism GO:0046961
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
|
9 | P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) |
|
Proton-transporting ATPase activity, rotational mechanism GO:0046961
Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
|
9 | P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Vacuolar transport GO:0007034
The directed movement of substances into, out of or within a vacuole.
|
9 | P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) |
|
Vacuolar transport GO:0007034
The directed movement of substances into, out of or within a vacuole.
|
9 | P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) P32366 (/IMP) |
|
Vacuolar acidification GO:0007035
Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.
|
9 | P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) |
|
Insulin receptor signaling pathway GO:0008286
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
|
4 | Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) |
|
Regulation of macroautophagy GO:0016241
Any process that modulates the frequency, rate or extent of macroautophagy.
|
4 | Q8N8Y2 (/NAS) Q8N8Y2 (/NAS) Q8N8Y2 (/NAS) Q8N8Y2 (/NAS) |
|
Transferrin transport GO:0033572
The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
4 | Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) |
|
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
4 | Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) |
|
Phagosome acidification GO:0090383
Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion.
|
4 | Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) |
|
Vacuolar proton-transporting V-type ATPase complex assembly GO:0070072
The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.
|
2 | A0A1D8PKX3 (/IMP) A0A1D8PKX3 (/IMP) |
There are 21 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Vacuolar proton-transporting V-type ATPase, V0 domain GO:0000220
The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.
|
9 | P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) P32366 (/TAS) |
|
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
|
9 | P32366 (/HDA) P32366 (/HDA) P32366 (/HDA) P32366 (/HDA) P32366 (/HDA) P32366 (/HDA) P32366 (/HDA) P32366 (/HDA) P32366 (/HDA) |
|
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
|
9 | P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) P32366 (/IDA) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
5 | Q5FVL0 (/IDA) Q8N8Y2 (/IDA) Q8N8Y2 (/IDA) Q8N8Y2 (/IDA) Q8N8Y2 (/IDA) |
|
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
|
4 | Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
4 | Q8N8Y2 (/IDA) Q8N8Y2 (/IDA) Q8N8Y2 (/IDA) Q8N8Y2 (/IDA) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
4 | Q2KJB6 (/ISS) Q5FVL0 (/ISS) Q5R7B7 (/ISS) Q80SY3 (/ISS) |
|
Vacuolar proton-transporting V-type ATPase complex GO:0016471
A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.
|
4 | Q8N8Y2 (/IDA) Q8N8Y2 (/IDA) Q8N8Y2 (/IDA) Q8N8Y2 (/IDA) |
|
Phagocytic vesicle membrane GO:0030670
The lipid bilayer surrounding a phagocytic vesicle.
|
4 | Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) Q8N8Y2 (/TAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
4 | Q8N8Y2 (/HDA) Q8N8Y2 (/HDA) Q8N8Y2 (/HDA) Q8N8Y2 (/HDA) |
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | P54641 (/IDA) |
|
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
1 | Q5FVL0 (/IDA) |
|
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
|
1 | Q80SY3 (/ISO) |
|
Early endosome GO:0005769
A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
|
1 | Q80SY3 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q80SY3 (/ISO) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | Q80SY3 (/ISO) |
|
Vacuolar proton-transporting V-type ATPase complex GO:0016471
A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.
|
1 | Q80SY3 (/ISO) |
|
Endocytic vesicle GO:0030139
A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
|
1 | P54641 (/IDA) |
|
Contractile vacuolar membrane GO:0031164
The lipid bilayer surrounding the contractile vacuole.
|
1 | P54641 (/TAS) |
|
Early phagosome GO:0032009
A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis.
|
1 | P54641 (/IDA) |
|
Phagocytic vesicle GO:0045335
A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
|
1 | P54641 (/HDA) |