The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"Multidrug efflux transporter AcrB transmembrane domain
".
FunFam 22: Dispatched RND transporter family member 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 0 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
There are 14 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
2 | A3KFU9 (/ISS) B9U3F2 (/ISS) |
|
Positive regulation of lipid metabolic process GO:0045834
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.
|
2 | A3KFU9 (/ISS) B9U3F2 (/ISS) |
|
Positive regulation of neural precursor cell proliferation GO:2000179
Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.
|
2 | A3KFU9 (/ISS) B9U3F2 (/ISS) |
|
Smoothened signaling pathway GO:0007224
A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
|
1 | Q9P2K9 (/NAS) |
|
Response to hormone GO:0009725
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
|
1 | B9U3F2 (/IEP) |
|
Regulation of lipid transport GO:0032368
Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | Q9P2K9 (/NAS) |
|
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
|
1 | B9U3F2 (/IDA) |
|
Cholesterol homeostasis GO:0042632
Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
|
1 | Q9P2K9 (/ISS) |
|
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
1 | Q9P2K9 (/IDA) |
|
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
1 | A3KFU9 (/ISO) |
|
Positive regulation of lipid metabolic process GO:0045834
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.
|
1 | Q9P2K9 (/IDA) |
|
Positive regulation of lipid metabolic process GO:0045834
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.
|
1 | A3KFU9 (/ISO) |
|
Positive regulation of neural precursor cell proliferation GO:2000179
Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.
|
1 | Q9P2K9 (/IDA) |
|
Positive regulation of neural precursor cell proliferation GO:2000179
Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.
|
1 | A3KFU9 (/ISO) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
2 | B9U3F2 (/NAS) Q9P2K9 (/NAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9P2K9 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | A3KFU9 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | A3KFU9 (/ISS) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | B9U3F2 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | Q9P2K9 (/ISS) |
|
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
1 | B9U3F2 (/IDA) |
|
Nuclear membrane GO:0031965
Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
|
1 | Q9P2K9 (/ISS) |
