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CATH Superfamily 1.20.1640.10

Multidrug efflux transporter AcrB transmembrane domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Multidrug efflux transporter AcrB transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Cation efflux system protein CusA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Copper ion transmembrane transporter activity GO:0005375
Enables the transfer of copper (Cu) ions from one side of a membrane to the other.
 23 P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI)
(13 more)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
 23 P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI)
(13 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 23 P38054 (/IPI) P38054 (/IPI) P38054 (/IPI) P38054 (/IPI) P38054 (/IPI) P38054 (/IPI) P38054 (/IPI) P38054 (/IPI) P38054 (/IPI) P38054 (/IPI)
(13 more)
Silver ion transmembrane transporter activity GO:0015080
Enables the transfer of silver (Ag) ions from one side of a membrane to the other.
 23 P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP)
(13 more)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cellular copper ion homeostasis GO:0006878
Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
 23 P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI)
(13 more)
Response to silver ion GO:0010272
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.
 23 P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP)
(13 more)
Response to silver ion GO:0010272
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.
 23 P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP)
(13 more)
Detoxification of copper ion GO:0010273
Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.
 23 P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI)
(13 more)
Silver ion transport GO:0015673
The directed movement of silver (Ag) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
 23 P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP)
(13 more)
Plasma membrane copper ion transport GO:0015679
The directed movement of copper ions across the plasma membrane.
 23 P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI)
(13 more)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
 23 P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP) P38054 (/IEP)
(13 more)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
 23 P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP) P38054 (/IMP)
(13 more)
Copper ion export GO:0060003
The directed movement of copper ions out of a cell or organelle.
 23 P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI) P38054 (/IGI)
(13 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
 23 P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA)
(13 more)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
 23 P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA) P38054 (/IDA)
(13 more)