The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:
"ABC transporter type 1, transmembrane domain
".
FunFam 27: ATP-binding cassette subfamily C member 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Efflux transmembrane transporter activity GO:0015562
Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.
|
5 | A0A2R8Q6E0 (/IDA) B2LUM7 (/IDA) F1QIK5 (/IDA) M1FT22 (/IDA) Q8QFL6 (/IDA) |
|
Prostaglandin transmembrane transporter activity GO:0015132
Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
|
3 | B9EKC2 (/ISO) E9Q236 (/ISO) Q3TZN9 (/ISO) |
|
Xenobiotic transmembrane transporter activity GO:0042910
Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
|
3 | B9EKC2 (/TAS) E9Q236 (/TAS) Q3TZN9 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | O15439 (/IPI) |
|
Prostaglandin transmembrane transporter activity GO:0015132
Enables the transfer of prostaglandins from one side of a membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
|
1 | Q8QFL6 (/IDA) |
|
Ion transmembrane transporter activity, phosphorylative mechanism GO:0015662
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.
|
1 | O15439 (/TAS) |
|
15-hydroxyprostaglandin dehydrogenase (NAD+) activity GO:0016404
Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+.
|
1 | O15439 (/NAS) |
There are 17 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Detoxification GO:0098754
Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
|
5 | A0A2R8Q6E0 (/IDA) B2LUM7 (/IDA) F1QIK5 (/IDA) M1FT22 (/IDA) Q8QFL6 (/IDA) |
|
Detoxification GO:0098754
Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
|
5 | A0A2R8Q6E0 (/IMP) B2LUM7 (/IMP) F1QIK5 (/IMP) M1FT22 (/IMP) Q8QFL6 (/IMP) |
|
Regulation of cilium assembly GO:1902017
Any process that modulates the frequency, rate or extent of cilium assembly.
|
5 | A0A2R8Q6E0 (/IMP) B2LUM7 (/IMP) F1QIK5 (/IMP) M1FT22 (/IMP) Q8QFL6 (/IMP) |
|
Drug transmembrane transport GO:0006855
The process in which a drug is transported across a membrane.
|
3 | B9EKC2 (/TAS) E9Q236 (/TAS) Q3TZN9 (/TAS) |
|
Response to organic substance GO:0010033
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
|
3 | F1LR52 (/IEP) F1M3J4 (/IEP) Q6QMG6 (/IEP) |
|
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
|
3 | F1LR52 (/IEP) F1M3J4 (/IEP) Q6QMG6 (/IEP) |
|
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
3 | F1LR52 (/IEP) F1M3J4 (/IEP) Q6QMG6 (/IEP) |
|
Prostaglandin secretion GO:0032310
The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.
|
3 | B9EKC2 (/ISO) E9Q236 (/ISO) Q3TZN9 (/ISO) |
|
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
3 | F1LR52 (/IEP) F1M3J4 (/IEP) Q6QMG6 (/IEP) |
|
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
|
3 | F1LR52 (/IMP) F1M3J4 (/IMP) Q6QMG6 (/IMP) |
|
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
|
3 | B9EKC2 (/ISO) E9Q236 (/ISO) Q3TZN9 (/ISO) |
|
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
3 | B9EKC2 (/ISO) E9Q236 (/ISO) Q3TZN9 (/ISO) |
|
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
2 | O15439 (/IMP) Q8QFL6 (/IMP) |
|
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
|
1 | O15439 (/TAS) |
|
Prostaglandin secretion GO:0032310
The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.
|
1 | O15439 (/IDA) |
|
Prostaglandin secretion GO:0032310
The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.
|
1 | Q8QFL6 (/IMP) |
|
Transmembrane transport GO:0055085
The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other.
|
1 | O15439 (/TAS) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
9 | A0A2R8Q6E0 (/IDA) B2LUM7 (/IDA) B9EKC2 (/IDA) E9Q236 (/IDA) F1QIK5 (/IDA) M1FT22 (/IDA) O15439 (/IDA) Q3TZN9 (/IDA) Q8QFL6 (/IDA) |
|
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
4 | F1LR52 (/IDA) F1M3J4 (/IDA) O15439 (/IDA) Q6QMG6 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | B9EKC2 (/ISO) E9Q236 (/ISO) Q3TZN9 (/ISO) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
3 | B9EKC2 (/ISO) E9Q236 (/ISO) Q3TZN9 (/ISO) |
|
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
3 | B9EKC2 (/ISO) E9Q236 (/ISO) Q3TZN9 (/ISO) |
|
Platelet dense granule membrane GO:0031088
The lipid bilayer surrounding the platelet dense granule.
|
3 | B9EKC2 (/ISO) E9Q236 (/ISO) Q3TZN9 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O15439 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | O15439 (/HDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | O15439 (/IDA) |
|
Apical plasma membrane GO:0016324
The region of the plasma membrane located at the apical end of the cell.
|
1 | Q6QMG6 (/IDA) |
|
Platelet dense granule membrane GO:0031088
The lipid bilayer surrounding the platelet dense granule.
|
1 | O15439 (/IDA) |
|
Platelet dense granule membrane GO:0031088
The lipid bilayer surrounding the platelet dense granule.
|
1 | O15439 (/TAS) |
