The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rhomboid-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 39: Derlin

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
11 Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA)
(1 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of cell cycle process GO:0010564
Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
11 Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA)
(1 more)
Ubiquitin-dependent ERAD pathway GO:0030433
The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein ubiquitination necessary for correct substrate transfer, transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
11 Q8IKV3 (/EXP) Q8IKV3 (/EXP) Q8IKV3 (/EXP) Q8IKV3 (/EXP) Q8IKV3 (/EXP) Q8IKV3 (/EXP) Q8IKV3 (/EXP) Q8IKV3 (/EXP) Q8IKV3 (/EXP) Q8IKV3 (/EXP)
(1 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
11 Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA)
(1 more)
Apicoplast GO:0020011
The plastid organelle found in apicomplexans.
11 Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA) Q8IKV3 (/IDA)
(1 more)