The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Rhomboid-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Rhomboid family protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Serine-type endopeptidase activity GO:0004252
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
6 P53259 (/IMP) P53259 (/IMP) P53259 (/IMP) P53259 (/IMP) P53259 (/IMP) P53259 (/IMP)

There are 4 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Signal peptide processing GO:0006465
The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.
6 P53259 (/IMP) P53259 (/IMP) P53259 (/IMP) P53259 (/IMP) P53259 (/IMP) P53259 (/IMP)
Regulation of mitochondrion organization GO:0010821
Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
6 P53259 (/IMP) P53259 (/IMP) P53259 (/IMP) P53259 (/IMP) P53259 (/IMP) P53259 (/IMP)
Signal peptide processing GO:0006465
The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.
1 O14364 (/ISO)
Mitochondrion organization GO:0007005
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
1 O14364 (/ISO)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
6 P53259 (/IDA) P53259 (/IDA) P53259 (/IDA) P53259 (/IDA) P53259 (/IDA) P53259 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 O14364 (/HDA)