CATH Superfamily 1.20.1530.20
The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 15: Na(+)/H(+) antiporter 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sodium:proton antiporter activity GO:0015385
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
|
4 | Q99271 (/IDA) Q99271 (/IDA) Q99271 (/IDA) Q99271 (/IDA) |
|
Cation:cation antiporter activity GO:0015491
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out).
|
4 | Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) |
|
Sodium:proton antiporter activity GO:0015385
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
|
3 | Q5AWT0 (/IMP) Q5AWT0 (/IMP) Q5AWT0 (/IMP) |
|
Potassium:proton antiporter activity GO:0015386
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in).
|
2 | Q6FJQ4 (/IDA) Q6FJQ4 (/IDA) |
|
Cation efflux transmembrane transporter activity GO:0046583
Enables the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane.
|
2 | Q6FJQ4 (/IDA) Q6FJQ4 (/IDA) |
|
Sodium:proton antiporter activity GO:0015385
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
|
1 | O14123 (/ISO) |
There are 10 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Potassium ion export across plasma membrane GO:0097623
The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.
|
6 | Q6FJQ4 (/IMP) Q6FJQ4 (/IMP) Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) |
|
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
|
4 | Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) |
|
Cellular monovalent inorganic cation homeostasis GO:0030004
Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell.
|
4 | Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) |
|
Cellular potassium ion homeostasis GO:0030007
Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell.
|
4 | Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) |
|
Sodium ion export across plasma membrane GO:0036376
The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.
|
4 | Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) Q99271 (/IMP) |
|
Cellular ion homeostasis GO:0006873
Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
|
3 | Q5AWT0 (/IMP) Q5AWT0 (/IMP) Q5AWT0 (/IMP) |
|
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
2 | Q6FJQ4 (/IDA) Q6FJQ4 (/IDA) |
|
Cellular potassium ion homeostasis GO:0030007
Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell.
|
2 | Q6FJQ4 (/IDA) Q6FJQ4 (/IDA) |
|
Potassium ion homeostasis GO:0055075
Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.
|
2 | Q6FJQ4 (/IMP) Q6FJQ4 (/IMP) |
|
Sodium ion export across plasma membrane GO:0036376
The directed movement of sodium ions from inside of a cell, across the plasma membrane and into the extracellular region.
|
1 | O14123 (/IC) |
There are 4 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
6 | Q6FJQ4 (/IDA) Q6FJQ4 (/IDA) Q99271 (/IDA) Q99271 (/IDA) Q99271 (/IDA) Q99271 (/IDA) |
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
4 | Q99271 (/HDA) Q99271 (/HDA) Q99271 (/HDA) Q99271 (/HDA) |
|
Membrane raft GO:0045121
Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
|
4 | Q99271 (/IDA) Q99271 (/IDA) Q99271 (/IDA) Q99271 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | O14123 (/ISO) |
